215178-71-5

Upstream product

• 183274-53-5 6-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,5-dihydro-3-iodo-4H-pyrazolo<3,4-d>pyrimidin-4-one 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 215178-27-1 1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,5-dihydro-3-iodo-6-[(2-methylpropanoyl)amino]-4H-pyrazolo[3,4-d]pyrimidin-4-one 

Downstream Products

• 252761-83-4 1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-erythro-pentofuranosyl]-3-(hex-1-ynyl)-1,5-dihydro-6-[(2-methylpropanoyl)amino]-4H-pyrazolo[3,4-d]pyrimidin-4-one 

Relevant academic research and scientific papers

Stabilisation of duplex DNA by 7-halogenated 8-aza-7-deazaguanines

Oligonucleotides containing 7-halogenated 8-aza-7-deaza-2'-deoxyguanosine (c7z8Gd) derivatives such as d(Br7c7z8G-C)4 8 (Tm = 88 deg C) and d(I7c7z8/s

Oligonucleotides containing pyrazolo[3,4-d]pyrimidines: The influence of 7-substituted 8-aza-7-deaza-2'-deoxyguanosines on the duplex structure and stability

Oligonucleotides containing 7-substituted 8-aza-7-deazaguanines (=6- amino-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones) were prepared by automated solid-phase synthesis. A series of 7-alkynylated 8-aza-7-deaza-2'- deoxyguanosines (see 4a-d) were synthe