215179-91-2

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 74124-56-4 (3S)-1,4-diacetyl-3-methylpiperazine-2,5-dione 
• 4526-77-6 (S)-3-methyl-2,5-piperazinedione 
• 65671-83-2 (N-(tert-butoxycarbonyl)-L-alaninyl)glycine ethyl ester 

Downstream Products

• 215179-95-6 (S,Z)-3-benzylidene-6-methylpiperazine-2,5-dione 
• 6230-11-1 O-Methyltyrosine 
• 215180-03-3 (S)-1-(2-Azido-benzoyl)-3-[1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-6-methyl-piperazine-2,5-dione 
• 215180-01-1 (S)-3,6-Diethoxy-2-[1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-5-methyl-2,5-dihydro-pyrazine 
• 215179-99-0 (S)-5-Ethoxy-6-[1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-3-methyl-3,6-dihydro-1H-pyrazin-2-one 
• 215179-97-8 (6S,3Z)-1-acetyl-6-methyl-3-(p-methoxybenzylidene)-5-thioxopiperazin-2-one 

Relevant academic research and scientific papers

Synthesis of Unusual Aromatic L-Amino Acids by Asymmetric Hydrogenation of Cyclic Dehydrodipeptides

To prepare L-Tyr(Me) and L-Amp (L-2-amino-5-(p-methoxyphenyl)pentanoic acid), their precursors cyclo(-ΔTyr(Me)-L-Ala-) and cyclo(-ΔAmp-L-Ala-) were hydrogenated in N,N-dimethylformamide.The content of LL isomers in the hydrogenated products was over 94percent.Mild acid hydrolysis of the hydrogenated products and subsequent recrystallization gave pure L-Tyr(Me) and L-Amp.

Comparative study of synthetic approaches to 1- arylmethylenepyrazino[2,1-b]quinazoline-3,6-diones

The transformation of 3-arylmethylenepiperazine-2,5-diones (1) into 1- arylmethylene-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones (2) was studied. Four synthetic methods were compared, namely direct condensation with the product of the reaction be