215433-19-5

Basic information

• Product Name: 7-BROMO-5-CHLORO-2-OXINDOLE
• Synonyms: 7-BROMO-5-CHLORO-2-OXINDOLE;7-Bromo-5-chloroindolin-2-one;7-bromo-5-chloro-2-indolinone;7-bromo-5-chloro-1,3-dihydroindol-2-one
• CAS NO: 215433-19-5
• Molecular Formula: C8H5BrClNO
• Molecular Weight: 246.49
• Mol File: 215433-19-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 7-BROMO-5-CHLORO-2-OXINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BROMO-5-CHLORO-2-OXINDOLE(215433-19-5)
• EPA Substance Registry System: 7-BROMO-5-CHLORO-2-OXINDOLE(215433-19-5)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 215433-19-5(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
7-Bromo-5-chloro-2-oxindole is used as a key intermediate in the development of pharmaceuticals and drug discovery. Its unique chemical structure allows it to be a promising candidate for the design and synthesis of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Organic Synthesis:
7-Bromo-5-chloro-2-oxindole serves as a valuable building block in organic synthesis for the creation of more complex molecules. Its presence of bromine and chlorine atoms facilitates further chemical reactions and modifications, enabling the synthesis of a wide range of advanced organic compounds with diverse applications in various industries.

Upstream product

• 17630-75-0 5-chloro-indolin-2-one 

Relevant articles and documents

Prodrugs of a 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Combination therapy for the treatment of cancer

The present invention relates to methods for treatment or prevention of neoplasia disorders using protein tyrosine kinase inhibitors in combination with cyclooxygenase inhibitors, in particular cyclooxygenase-2 selective inhibitors.

3-(cycloalkanoheteroarylidenyl)-2-indolinone protein tyrosine kinase inhibitors

The present invention relates to novel 3-(cycloalkano-heteroarylidenyl)-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which are expected to modulate the activity of protein tyrosine kinases and therefore to be useful in the prevention and treatment of protein tyrosine kinase related cellular disorders such as cancer.

Pyrrole substituted 2-indolinone protein kinase inhibitors

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

3-heteroarylidene-2-indolinone protein kinase inhibitors

The present invention relates to novel 3-heteroarylidene-2-indolinone compounds and physiologically acceptable salts thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

3-(cycloalkanoheteroarylidenyl)-2- indolinone protein tyrosine kinase inhibitors

The present invention relates to novel 3-(cycloalkanoheteroarylidenyl)-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which are expected to modulate the activity of protein tyrosine kinases and therefore to be useful in the prevention and treatment of protein tyrosine kinase related cellular disorders such as cancer.