215451-97-1

Upstream product

• 3164-13-4 2-(4-bromophenyl)-1,3-benzoxazole 
• 117649-27-1 2-(4-bromo-benzylidenamino)-phenol 
• 225100-45-8 2-<4-(3-hydroxy-3-methylbutyne-1-yl)phenyl>benzoxazole 
• 95-55-6 2-amino-phenol 
• 1122-91-4 4-bromo-benzaldehyde 
• 109113-66-8 2-[4-phenylethynyl]phenylbenzoxazole 
• 1956-30-5 3',5'-O-diacetyl-5-iodo-2'-deoxyuridine 

Downstream Products

• 225100-57-2 5'-O-(4,4'-dimethoxytrityl)-5-<4-(benzoxazolyl)phenyl>ethynyl-2'-deoxyuridine 
• 225100-55-0 5-<4-(2-benzoxazolyl)phenyl>ethynyl-2'-deoxyuridine 

Relevant academic research and scientific papers

Reagents for introducing a fluorescent deoxyuridine 2-phenylbenzoxazole derivative into oligonucleotides

Using the Heck-Sonogashira reaction, a new fluorescent nucleoside, 5-[4-(2-benzoxazolyl)phenyl]ethynyl-2′-deoxyuridine, was synthesized and converted into oligonucleotide-labeling reagents, namely, 3′-phosphoramidite and a functionalized solid support.

New fluorescent nucleoside derivatives - 5-alkynylated 2'-deoxyuridines

Four fluorescent nucleosides, 5-(4-pyrenylethynyl)-, 5-(1- pyrenylbutadiynyl)-, 5-(3-perylenylethynyl)-, and 5-[4-(2- benzoxazolyl)phenylethynyl]-2'deoxyuridines, were synthesized.