215461-25-9Relevant academic research and scientific papers
Metallation of benzylic amines via amine-borane complexes
Ebden, Mark R.,Simpkins, Nigel S.,Fox, David N.A.
, p. 12923 - 12952 (1998)
Formation of borane complexes of N,N-dimethylbenzylamine, N,N- dimethyl(1-naphthyl)methylamine, N,N-dimethyl(2-naphthyl)methylamine, N- methyltetrahydroisoquinoline and N-methylisoindoline facilitates regioselective metallation of these systems using BuLi, giving intermediate benzylic anions which react with a range of electrophiles to give products in good yield.
