21554-41-6

Usage

Uses

Used in Pharmaceutical Industry:
2-Methylsulfonyl-6-nitrobenzothiazole is used as a precursor in the synthesis of various pharmaceuticals, leveraging its reactive functional groups to facilitate the creation of diverse medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Methylsulfonyl-6-nitrobenzothiazole serves as a starting material for the development of agrochemicals, potentially contributing to the production of pesticides and other agricultural products.
Used in Dye and Pigment Production:
2-Methylsulfonyl-6-nitrobenzothiazole is utilized in the manufacturing process of dyes and pigments, capitalizing on its chemical properties to produce a range of colorants for different applications.
It is crucial to handle 2-Methylsulfonyl-6-nitrobenzothiazole with caution due to its potential hazards and toxic properties, ensuring safety in its applications across various industries.

InChI:InChI=1/C8H6N2O4S2/c1-16(13,14)8-9-6-3-2-5(10(11)12)4-7(6)15-8/h2-4H,1H3

Upstream product

• 4845-58-3 2-mercapto-6-nitrobenzothiazole 
• 3621-99-6 2-methylthio-6-nitrobenzothiazole 
• 121579-06-4 bis(6-nitrobenzo[d]thiazol-2-yl)disulfide 
• 4845-58-3 6-nitrobenzo[d]thiazole-2(3H)-thione 

Downstream Products

• 34976-39-1 Tioxacin 
• 28620-12-4 6-nitro-2(3H)-benzothiazolone 

Relevant academic research and scientific papers

Divergent S- And C-Difluoromethylation of 2-Substituted Benzothiazoles

Two unprecedented and complementary synthetic strategies for S- and C-difluoromethylation of 2-substituted benzothiazoles have been developed by taking advantage of the remarkably different reactivity of CF2H- and 2-PySO2CF2- nucleophiles. A variety of structurally diverse difluoromethyl 2-isocyanophenyl sulfides and 2-difluoromethylated benzothiazoles were synthesized with these two new synthetic protocols.

Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling

Heteroaromatic sulfones react with cysteine via nucleophilic aromatic substitution, providing a mechanistically selective and irreversible scaffold for cysteine conjugation. Here we evaluate a library of heteroaromatic sulfides with different oxidation st

Radical Fluoroalkylation of Isocyanides with Fluorinated Sulfones by Visible-Light Photoredox Catalysis

The radical fluoroalkylation of isocyanides with fluorinated sulfones is enabled by visible-light photoredox catalysis. A wide range of readily available mono-, di-, and trifluoromethyl heteroaryl sulfones can thus be used as efficient radical fluoroalkylation reagents under mild conditions. This method not only describes a new synthetic application of fluorinated sulfones, but also provides a new route to fluoroalkyl radicals.