215649-81-3 Usage
General Description
1-(3-Bromophenyl)-piperazin-2-one hydrochloride is a chemical compound that consists of a piperazine ring with a phenyl group and a bromine atom attached to it. It is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and compounds. This chemical has the potential to exert various pharmacological effects, including being a potential antipsychotic and anxiolytic agent. It also has potential applications in the treatment of central nervous system disorders and mood disorders. Additionally, it is important to handle this compound with caution, as it is considered to be hazardous and can cause irritation to the skin, eyes, and respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 215649-81-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,6,4 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 215649-81:
(8*2)+(7*1)+(6*5)+(5*6)+(4*4)+(3*9)+(2*8)+(1*1)=143
143 % 10 = 3
So 215649-81-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H11BrN2O.ClH/c11-8-2-1-3-9(6-8)13-5-4-12-7-10(13)14;/h1-3,6,12H,4-5,7H2;1H
215649-81-3Relevant articles and documents
Efficient synthesis of N-arylpiperazinones via a selective intramolecular Mitsunobu cyclodehydration
Weissman, Steven A.,Lewis, Stephanie,Askin, David,Volante,Reider, Paul J.
, p. 7459 - 7462 (2007/10/03)
A practical two pot synthesis of N-arylpiperazinones from the corresponding aniline is described. The key transformation is a selective intramolecular Mitsunobu cyclodehydration of an amidoalcohol intermediate. A series of N-arylpiperazinones were prepared in yields up to 89%.