215655-77-9

Upstream product

• 3757-76-4 sodium 2,4-dichlorophenolate 
• 187973-23-5 chloro-acetic acid 1-(dimethoxy-phosphoryl)-butyl ester 
• 23054-81-1 dimethyl α-hydroxybutylphosphonate 
• 774-74-3 2-(2,4-dichlorophenoxy)acetyl chloride 
• 94-75-7 2,4-Dichlorophenoxyacetic acid 

Downstream Products

• 1097934-86-5 sodium hydrogen (1-{[2-(2,4-dichlorophenoxy)acetyl]oxy}butyl)phosphonate 

Relevant academic research and scientific papers

Synthesis and herbicidal activities of methyl-1-(2,4- dichlorophenoxyacetoxy)alkylphosphonate monosalts

A series of 1-(2,4-dichlorophenoxyacetoxy)alkylphosphonic acid dimethyl esters 5 and its corresponding phosphonate monosalts 6 were synthesized as potential herbicide. The phosphonate monosalts can be prepared from 1-(2,4-dichlorophenoxyacetoxy)alkylphosphonic acid dimethyl esters 5, which were synthesized by the condensation of O,O-dimethyl-1-hydroxyalkylphosphonates with dichlorophenoxyacetic chloride. This method provides a simple and efficient procedure for the synthesis of phosphonate derivatives containing sensitive groups to acid, base or water such as carboxylate ester bond; and the herbicidal activity of title compounds was evaluated in a set of experiments in greenhouse. Most of the compounds exhibited notable herbicidal activity.

Synthesis and herbicidal activities of sodium hydrogen 1-(substituted phenoxyacetoxy)alkylphosphonates

A series of sodium hydrogen 1-(substituted phenoxyacetoxy) alkylphosphonates was designed and synthesized. The test for herbicidal activity indicated that most of the phosphonates (8) possessed excellent postemergence herbicidal activities against broadleaf weeds. Especially, 8f and 8g showed the best herbicidal activity against rape and amaranth with more than 95% inhibitory rate. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

Synthesis and herbicidal activities of lithium or potassium hydrogen 1-(substituted phenoxyacetoxy)alkylphosphonates

A series of lithium or potassium hydrogen 1-(substituted phenoxyacetoxy)alkylphosphonates were designed and synthesized. All the title compounds were identified by IR, 1H NMR, and 31P NMR, some of them were further analyzed by MS and elemental analyses. The test for herbicidal activity indicated that most of the phosphonates (8) possessed excellent postemergence herbicidal activities against broadleaf weeds. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

Simple and improved preparation of α-oxophosphonate monolithium salts

Some α-OxoPhosphonate monolithium salts were synthesized by a facile one-step procedure. In this way, α-(2,4-dichlorophenoxyacetoxy)alkyl phosphonic acid dimethyl esters 5 can be transformed into the corresponding phosophonate monolithium salts 6 without influence on the carboxylic ester group under mild conditions.

Synthesis and dealkylation of 1 -(dichloro-phenoxyacetoxy) alkyl phosphonates

Using the silylation procedure with chlorotrimethylsilane/sodium iodide followed by alcoholysis, 1-(dichlorophenoxy acetoxy)alkyl phosphonic acid dimethyl esters can be transformed into the parent phosphonic acids without influence on carboxylate ester group.