215657-34-4

Upstream product

• 98611-90-6 N-(2-fluorophenyl)methanesulfonamide 
• 501-53-1 benzyl chloroformate 
• 348-54-9 2-Fluoroaniline 

Downstream Products

• 84477-85-0 benzyl 3-methylpiperazine-1-carboxylate 
• 123660-45-7 (α-methylbenzyl)carbamic acid benzyl ester 
• 39896-97-4 benzyl-carbamic acid benzyl ester 
• 81616-15-1 N-benzyl-N-methylcarbamic acid benzyl ester 

Relevant academic research and scientific papers

Studies on development of sufficiently chemoselective N-acylation reagents: N-Acyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamides

A variety of storable N-acyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamides (4a-e) prepared from N-2,3,4,5,6-pentafluorophenylmethanesulfonamide (3), have been developed after systematic research on the structure-reactivity relationship and were found to serve as N-acylation reagents exhibiting sufficiently good chemoselectivity. (C) 2000 Elsevier Science Ltd.

A versatile synthon for chemoselective N-acylation reagents, 2-fluoro-N-mesylaniline

2-Fluoro-N-mesylaniline 3b undergoes various N-acylalions easily to give 2-fluoro-N-acyl-N-mesylanilines 4b-8b, which function as good chemoselective N-acylation reagents, especially for benzyloxycarbonylation.