2157-47-3

Usage

Uses

Used in Perfume and Flavor Industries:
(2Z)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-one oxime is used as a fragrance and flavoring agent in the perfume and flavor industries due to its minty or camphor-like odor.
Used in Pharmaceutical Industry:
(2Z)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-one oxime is used as a pharmaceutical agent for its antimicrobial and insecticidal properties.
Used in Drug Synthesis:
(2Z)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-one oxime is used as a chiral building block in organic chemistry for the synthesis of new drugs.

Upstream product

• 1195-79-5 1,3,3-trimethyl-2-norbornanone 
• 875-06-9 1,3,3-trimethyl-bicyclo[2.2.1]heptane-2-thione 
• 7803-49-8 hydroxylamine 
• 4695-62-9 fenchone 
• 64-17-5 ethanol 
• 56022-41-4 nitro-(1,3,3-trimethyl-[2]norbornyliden)-amine 
• 18492-37-0 (+/-)-fenchone 
• 7787-20-4 (-)-1,3,3-trimethyl-2-norbornanone 

Downstream Products

• 2157-47-3 fenchone oxime 
• 192702-77-5 (1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amide 
• 1195-79-5 1,3,3-trimethyl-2-norbornanone 
• 13180-66-0 1,3,3-Trimethyl-bicyclo[2.2.1]heptan-2-one O-(5-chloro-2,4-dinitro-phenyl)-oxime 

Relevant academic research and scientific papers

Multinuclear Magnetic Resonance Study of 1,3,3-Trimethylbicycloheptan-2-one (Fenchone) Oxime, Its Five Monochloro Derivatives and a Dehydrochlorination Product

Fenchone oxime, 5-exo-chlorofenchone oxime, 6-exo-chlorofenchone oxime, 7-anti-chlorofenchone oxime, 8-chlorofenchone oxime, 9-chlorofenchone oxime and a dehydrochlorination product of 10-chlorofenchone oxime were synthesized from fenchone and the corresponding chlorofenchones.The 1H, 13C and 17O NMR spectra of the oximes and the dehydrochlorination product were recorded.The NMR data were compared with the corresponding parameters obtained earlier for fenchone and monochlorofenchones in order to determine the differences between the carbonyl and oxime substituents from the NMR spectroscopic point of view, and to assign the stereochemistry of the oxime group.The stereochemistry could not, however, be assigned solely by NMR spectroscopy.

Synthesis, docking study and β-Adrenoceptor activity of some new oxime ether derivatives

A new series of oxime ethers 4a-z was designed and synthesized to test the blocking activity against β1 and β2-Adrenergic receptors. Docking of these ether derivatives into the active site of the identified 3D structures of β1 and β2-Adrenergic receptors

N-tert-Butyl-N-chlorocyanamide: A new reagent for the efficient preparation of gem-chloronitroso compounds

A new reagent for the efficient preparation of gem-chloronitroso compounds has been developed. The reaction of ketoximes with N-tert-butyl-N- chlorocyanamide takes place instantaneously in carbon tetrachloride at room temperature with excellent yields under mild conditions.

Structure/Odour Relationships of Bicyclic Oximes

Bicycloheptan-2-one Derivatives, Bridge Homologated Norbornanes, Cassis Odour, Geminal Dimethyl Group Numerous bicyclic oximes are synthesized and for the first time the influence not only of the bicyclic nucleus but also of the α-geminal dimethyl group on the odourous character studied.The pleasant cassis odour of camphenilonoxime seems remarkable.