2157-56-4

Usage

Chemical Properties

white crystalline powder

InChI:InChI=1/C5H10N2O2/c1-4(6-8)3-5(2)7-9/h8-9H,3H2,1-2H3/b6-4-,7-5u

Upstream product

• 2010-12-0 3,4-dimethylisoxazole 
• 110-44-1 sorbic Acid 
• 123-54-6 acetylacetone 
• 1118-66-7 4-amino-3-penten-2-one 
• 7803-49-8 hydroxylamine 
• 110-44-1 hexa-2,4-dienoic acid 

Downstream Products

• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 591-05-9 2,4-diaminopentane 
• 591-05-9 2,4-diaminopentane 
• 591-05-9 2,4-n-meso-diaminopentane 
• 34998-98-6 (2R,4R)-pentane-2,4-diamine 
• 34998-99-7 (2S,4S)-pentane-2,4-diamine 
• 123-54-6 acetylacetone 
• 2010-12-0 3,4-dimethylisoxazole 
• 7803-49-8 hydroxylamine 
• 101204-19-7 racem.-2.4-bis-benzamino-pentane 
• 91-19-0 2,3-diethynylquinoxaline 

Relevant academic research and scientific papers

High-Throughput Screening of Earth-Abundant Water Reduction Catalysts toward Photocatalytic Hydrogen Evolution

Noble-metal photosensitizers and water reduction co-catalysts (WRCs) still present the highest activity in homogeneous photocatalytic hydrogen production. The search for earth-abundant alternatives is usually limited by the time required to screen new catalyst combinations; however, here, we utilize newly designed and developed high-throughput photoreactors for the parallel synthesis of novel WRCs and colorimetric screening of hydrogen evolution. This unique approach allowed rapid optimization of photocatalytic water reduction using the organic photosensitizer Eosin Y and the archetypal cobaloxime WRC [Co(GL1)2pyCl], where GL1 is dimethylglyoxime and py is pyridine. Subsequent combinatorial synthesis generated 646 unique cobalt complexes of the type [Co(LL)2pyCl], where LL is a bidentate ligand, that identified promising new WRC candidates for hydrogen production. Density functional theory (DFT) calculations performed on such cobaloxime derivative complexes demonstrated that reactivity depends on hydride affinity. Alkyl-substituted glyoximes were necessary for hydrogen production and showed increased activity when paired with ligands containing strong hydrogen-bond donors.

Synthesis of ketoximes via a solvent-assisted and robust mechanochemical pathway

A versatile and robust mechanochemical route to ketone-oxime conversions has been established for a broad range of ketones via a simple mortar-pestle grinding method. The relative reactivity of aldehydes vs. ketones under these conditions has also been explored, along with an examination of the possible connection between reactivity and electronic substituent effects.

Catalytic effect of wet molecular sieve 3A in dry media on syntheses of oximes and 1,3-dioximes

A simple, efficient and eco-friendly method has been developed for the condensation of hydroxylamine hydrochloride with aldehydes, ketones and 1,3-diketones in the presence of powdered molecular sieves (3A) as catalyst. Aldoximes, ketoximes and 1,3-dioximes were obtained in excellent yields.

Dioximes of 1,3-diketones in the trofimov reaction: New 3-substituted pyrroles

Dioximes of 1,3-diketones enter into the Trofimov reaction forming pyrroles containing an acyl or an O-vinyloxime substituent in position 3 of the pyrrole. In the case of sterically hindered dioximes the main reaction products are isoxazoles. 2005 Springer Science+Business Media, Inc.

Microwave enhanced synthesis of oximes from ketones

Microwave enhanced synthesis of oximes from ketones in high yields is reported.