2157-58-6

Basic information

• Product Name: (NE)-N-(3,5,5-trimethyl-1-cyclohex-2-enylidene)hydroxylamine
• Synonyms: (NE)-N-(3,5,5-trimethyl-1-cyclohex-2-enylidene)hydroxylamine
• CAS NO: 2157-58-6
• Molecular Formula: C₉H₁₅NO
• Molecular Weight: 153.2215
• Mol File: 2157-58-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 243.2°Cat760mmHg
• Flash Point: 136.7°C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 0.00552mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: (NE)-N-(3,5,5-trimethyl-1-cyclohex-2-enylidene)hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (NE)-N-(3,5,5-trimethyl-1-cyclohex-2-enylidene)hydroxylamine(2157-58-6)
• EPA Substance Registry System: (NE)-N-(3,5,5-trimethyl-1-cyclohex-2-enylidene)hydroxylamine(2157-58-6)

Safety Data

• Hazardous Substances Data: 2157-58-6(Hazardous Substances Data)

Usage

General Description

(NE)-N-(3,5,5-trimethyl-1-cyclohex-2-enylidene)hydroxylamine is a chemical compound with the molecular formula C10H17NO. It is a hydroxylamine derivative with a cyclohexene ring structure and three methyl substituents. (NE)-N-(3,5,5-trimethyl-1-cyclohex-2-enylidene)hydroxylamine is commonly used as a reagent in organic synthesis, particularly in the preparation of various heterocyclic compounds. It is also utilized in the pharmaceutical industry as a building block for the synthesis of potential drug candidates. Additionally, (NE)-N-(3,5,5-trimethyl-1-cyclohex-2-enylidene)hydroxylamine has been studied for its potential anti-inflammatory and anti-cancer properties, making it a subject of interest in medicinal chemistry research. Overall, this chemical compound has various applications and potential uses in different fields of science and industry.

InChI:InChI=1/C9H15NO/c1-7-4-8(10-11)6-9(2,3)5-7/h4,11H,5-6H2,1-3H3/b10-8-

Upstream product

• 78-59-1 3,5,5-Trimethylcyclohex-2-en-1-one 

Downstream Products

• 54920-32-0 (1S,2S,6R)-2,4,4-Trimethyl-7-aza-bicyclo[4.1.0]heptane 
• 54920-40-0 3,5,5-trimethyl-cyclohex-2-enylamine 
• 15901-42-5 cis-3,5,5-trimethylcyclohexylamine 
• 54920-32-0 trans-2,4,4-trimethyl-7-azabicyclo<4.1.0>heptane 
• 119990-58-8 C₁₆H₂₁NO₃S 
• 134734-56-8 (E)-O-acetyl 3,5,5-trimethyl-2-cyclohexene-1-one oxime 
• 134734-57-9 (Z)-O-acetyl 3,5,5-trimethyl-2-cyclohexene-1-one oxime 
• 1467-34-1 3',4',5'-trimethylacetanilide 
• 13194-17-7 3,5,5-Trimethyl-cyclohex-2-enone O-(5-isopropylamino-2,4-dinitro-phenyl)-oxime 
• 1247792-12-6 (E)-6-(dimethylaminomethyl)-3,5,5-trimethylcyclohex-2-en-1-one oxime hydrochloride 
• 1247792-15-9 (Z)-2-(dimethylaminomethyl)-3,5,5-trimethylcyclohex-2-en-1-one oxime hydrochloride 
• 1247792-01-3 (Z)-6-(dimethylaminomethyl)-3,5,5-trimethylcyclohex-2-en-1-one oxime hydrochloride 
• 1247792-04-6 (E)-2-(dimethylaminomethyl)-3,5,5-trimethylcyclohex-2-en-1-one oxime hydrochloride 
• 119990-61-3 1,3,3,5-Tetramethyl-1-(2-oxo-2-phenyl-ethyl)-2,3,4,7-tetrahydro-1H-azepinium; bromide 

Relevant articles and documents

Copper-catalyzed synthesis of thiazol-2-yl ethers from oxime acetates and xanthates under redox-neutral conditions

A novel copper-catalyzed annulation of oxime acetates and xanthates for the synthesis of thiazol-2-yl ethers with remarkable regioselectivity has been developed. Various oxime acetates, whether derived from aryl ketones or alkyl ketones, or natural product cores are suitable for this conversion. Unique dihydrothiazoles were also obtained when both reaction sites were methine. Mechanistic studies indicated that imino copper(iii) intermediates were involved. In addition, this protocol proceeded under redox-neutral conditions and did not require additives or ligands.

STEREOSELECTIVE ROUTE TO N-METHYL-2,3-CIS-DISUBSTITUTED PIPERIDINES

A new stereo-selective route to cis-disubstituted piperidines is presented in which the key step is a Stevens rearrangement with ring contraction.