21573-40-0

Upstream product

• 2944-49-2 2,3-dimethylanisole 
• 526-85-2 2,3,4-trimethylphenol 
• 74-88-4 methyl iodide 
• 75-77-4 chloro-trimethyl-silane 
• 95-48-7 ortho-cresol 
• 77-78-1 dimethyl sulfate 
• 38998-17-3 2,3-dimethyl-4-methoxybenzaldehyde 

Downstream Products

• 526-85-2 2,3,4-trimethylphenol 
• 73322-57-3 4-methoxy-1,2,3-benzenetricarboxylic acid 
• 855642-18-1 4-methoxy-2-methyl-isophthalic acid 
• 99180-01-5 6-bromo-2,3,4-trimethyl-phenol 
• 104296-16-4 (2,3,4-trimethyl-phenoxy)-acetic acid 
• 33931-27-0 4,4'-dithio-bis-(2-methyl-phenol) 

Relevant academic research and scientific papers

Volatiles from the hypoxylaceous fungi Hypoxylon griseobrunneum and Hypoxylon macrocarpum

The volatiles emitted by the ascomycetes Hypoxylon griseobrunneum and Hypoxylon macrocarpum (Hypoxylaceae, Xylariales) were collected by use of a closed-loop stripping apparatus (CLSA) and analysed by GC-MS. The main compound class of both species were polysubstituted benzene derivatives. Their structures could only be unambiguously determined by comparison to all isomers with different substitution patterns. The substitution pattern of the main compound from H. griseobrunneum, the new natural product 2,4,5-trimethylanisole, was explainable by a polyketide biosynthesis mechanism that was supported by a feeding experiment with (methyl-2H3)methionine.

Phenyl derivatives, their manufacture and use as pharmaceutical agents

This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.