21575-75-7Relevant academic research and scientific papers
Iodine-Catalyzed Synthesis of Substituted Furans and Pyrans: Reaction Scope and Mechanistic Insights
Pace, Domenic P.,Robidas, Rapha?l,Tran, Uyen P. N.,Legault, Claude Y.,Nguyen, Thanh Vinh
, p. 8154 - 8171 (2021/06/28)
Substituted pyrans and furans are core structures found in a wide variety of natural products and biologically active compounds. Herein, we report a practical and mild catalytic method for the synthesis of substituted pyrans and furans using molecular iodine, a simple and inexpensive catalyst. The method described is performed under solvent-free conditions at an ambient temperature and atmosphere, thus offering a facile and practical alternative to currently available reaction protocols. A combination of experimental studies and density functional theory calculations revealed interesting mechanistic insights into this seemingly simple reaction.
Platinum(II)-catalyzed reaction of γ,δ-ynones with alkenes for the construction of 8-oxabicyclo[3.2.1]octane skeletons: Generation of platinum-containing carbonyl ylides from acyclic precursors
Kusama, Hiroyuki,Ishida, Kento,Funami, Hideaki,Iwasawa, Nobuharu
supporting information; experimental part, p. 4903 - 4905 (2009/02/08)
(Chemical Equation Presented) Two types of bicycles can be prepared selectively by the title reaction, depending on whether or not a substituent is present at the propargylic position of the ynone substrate (see scheme). The cycloaddition of carbonyl ylid
