215808-73-4

Usage

Uses

Used in Organic Synthesis:
Methyl5-(2-Methoxy-2-oxoethyl)-2-Methyloxazole-4-carboxylate is used as a building block in organic synthesis for the creation of various complex organic compounds. Its versatile structure allows for the development of new molecules with specific properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl5-(2-Methoxy-2-oxoethyl)-2-Methyloxazole-4-carboxylate is utilized as a key component in the synthesis of a range of drugs and pharmaceutical compounds. Its chemical properties make it a valuable asset in the development of new medications.
Used as a Research Tool:
Methyl5-(2-Methoxy-2-oxoethyl)-2-Methyloxazole-4-carboxylate may also serve as a starting material in the production of other drugs, providing a foundation for further chemical modifications and enhancements. Additionally, it is employed as a research tool in chemical and pharmaceutical research to explore its properties and potential applications in drug discovery and development.

Upstream product

• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 868-09-7 2-hydroxyimino-3-oxo-pentanedioic acid dimethyl ester 
• 188657-38-7 dimethyl 2-acetamido-3-oxopentanedioate 

Downstream Products

• 1289571-56-7 6-(2-fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-2,5-dimethyl-4-oxo-4,5-dihydrooxazolo [4,5-c]pyridine-7-carboxamide 
• 1373868-80-4 6-(2-fluoro-4-iodophenylamino)-2,5-dimethyl-4-oxo-4,5-dihydrooxazolo[4,5-c]pyridine-7-carboxylic acid 
• 1400819-00-2 6-(2-fluoro-4-iodophenylamino)-2,5-dimethyl-4-oxo-N-(2-(vinyloxy)ethoxy)-4,5-dihydrooxazolo[4,5-c]pyridine-7-carboxamide 

Relevant academic research and scientific papers

Synthesis and reactions of a novel furo[3,4-d]oxazole

The synthesis of a novel furo[3,4-d]oxazole (7) starting from 2-hydroximino-3-oxopentanedioic acid dimethyl ester (4) and cycloadditions of 7 with dienophiles are reported. Density functional theoretical studies (B3LYP/6-31G) for various c-annulated furans (benzo[c]furan, furo[3,4-d]isoxazole, furo[3,4-f]oxazole, furo[3,4-c￡]thiazole, furo[3,4-6]indole) and their Diels-Aider reactions with model dienophiles (ethylene, acetylene) are in qualitative agreement with experimental data.

HETEROCYCLIC COMPOUNDS AS MEK INHIBITORS

The invention provides novel substituted heterocyclic compounds represented by Formula I and Formula II, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tauntomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans

NOVEL 6-ARYLAMINO PYRIDONE CARBOXAMIDE AS MEK INHIBITORS

The invention provides novel substituted 6-arylamino pyridone carboxamides represented by Formula I, or a pharmaceutically acceptable salt, solvate, poly- morph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans.