21591-86-6

Upstream product

• 53157-48-5 tert-butyl 2-(5-hydroxy-1H-indol-3-yl)ethylcarbamate 

Downstream Products

• 142363-38-0 (2S,4R)-2-<(5-hydroxy-1H-indol-3-yl)methyl>thiazolidine 
• 142363-37-9 (2R,4R)-2-<(5-hydroxy-1H-indol-3-yl)methyl>thiazolidine 
• 53157-48-5 tert-butyl 2-(5-hydroxy-1H-indol-3-yl)ethylcarbamate 
• 108560-71-0 tryptamine-4,5-dione 
• 3000-36-0 1-methyl-6-hydroxy-1,2,3,4-tetrahydro-β-carboline 
• 374680-35-0 3,4,5,6-tetrahydro-7-hydroxy-6-methyl-1H-azepino[5,4,3-cd]indole 
• 1002100-44-8 N-oleoylserotonin 
• 240124-73-6 N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)benzamide 
• 1262007-81-7 tert-butyl 2-(5-(3-cyano-4-isopropoxybenzyloxy)-1H-indol-3-yl)ethylcarbamate 
• 28026-16-6 3-(2-acetamidoethyl)-1H-indol-5-yl acetate 
• 1373764-85-2 C₂₇H₂₆N₂O₂ 
• 1373764-86-3 6-hydroxy-1-methyl-N-phenylacetyl-1,3,4,9-tetrahydro-β-carboline 
• 20776-45-8 5-benzyloxytryptamine 
• 17952-78-2 6-(benzyloxy)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole 

Relevant academic research and scientific papers

Preparation method of 5-hydroxytryptamine hydrochloride

The invention discloses a preparation method of 5-hydroxytryptamine hydrochloride, and particularly relates to a method for efficiently synthesizing the 5-hydroxytryptamine hydrochloride by taking 5-hydroxyindole and nitroethylene as raw materials through addition reaction and reduction reaction. The preparation method of the 5-hydroxytryptamine hydrochloride provided by the invention is a preparation method which is high in yield, low in cost, less in three wastes, good in product purity and suitable for industrialization.

Method for preparing 5-hydroxytryptamine hydrochloride by utilizing enzymatic fermentation liquor containing 5-hydroxytryptamine

The invention discloses a method for preparing 5-hydroxytryptamine hydrochloride from 5-hydroxytryptamine-containing enzymatic fermentation liquor, and relates to the technical field of 5-hydroxytryptamine extraction. The method comprises the following steps: concentrating 5-hydroxytryptamine-containing enzymatic fermentation liquor under reduced pressure, mixing the concentrated 5-hydroxytryptamine-containing enzymatic fermentation liquor with an organic solvent, sequentially dropwise adding triethylamine and BOC anhydride at low temperature, heating to 20-25 DEG C after dropwise adding is finished, reacting to obtain an N-BOC-5-hydroxytryptamine reaction solution, adding ethyl acetate, and extracting to obtain an ethyl acetate organic phase; adding ethyl acetate containing hydrochloric acid into the ethyl acetate organic phase for reaction, and performing suction filtration after the reaction is finished to obtain a 5-hydroxytryptamine hydrochloride crude product; and further purifying the obtained 5-hydroxytryptamine hydrochloride crude product to obtain 5-hydroxytryptamine hydrochloride. According t o the invention, high-purity 5-hydroxytryptamine hydrochloride is prepared by optimizing the method for purifying 5-hydroxytryptamine in an enzymatic fermentation liquor, so that the current situation that 5-hydroxytryptamine hydrochloride is difficult to prepare by simply extracting serotonin in the enzymatic fermentation liquor is changed.