215960-01-3Relevant academic research and scientific papers
Asymmetric synthesis of enantiomerically pure 7-isopropenyl-4a-methyl-3-methyleneoctahydrochromen-2-ones
Krawczyk, Henryk,Sliwinski, Marcin,Kedzia, Jacek,Wojciechowski, Jakub,Wolf, Wojciech M.
, p. 2712 - 2718 (2008/09/16)
Four stereoisomers of 7-isopropenyl-4a-methyl-3-methyleneoctahydrochromenon-2-one have been obtained for the first time. The key step of the synthesis involves asymmetric Michael addition of chiral enamines derived from dihydrocarvone to acrylate 1. Absolute configurations were established by X-ray analysis.
