21599-40-6Relevant articles and documents
Chiral Br?nsted Acid Catalyzed Dynamic Kinetic Asymmetric Hydroamination of Racemic Allenes and Asymmetric Hydroamination of Dienes
Lin, Jin-Shun,Li, Tao-Tao,Jiao, Guan-Yuan,Gu, Qiang-Shuai,Cheng, Jiang-Tao,Lv, Ling,Liu, Xin-Yuan
supporting information, p. 7092 - 7096 (2019/04/26)
The first highly efficient and practical chiral Br?nsted acid catalyzed dynamic kinetic asymmetric hydroamination (DyKAH) of racemic allenes and asymmetric hydroamination of unactivated dienes with both high E/Z selectivity and enantioselectivity are described herein. The transformation proceeds through a new catalytic asymmetric model involving a highly reactive π-allylic carbocationic intermediate, generated from racemic allenes or dienes through a proton transfer mediated by an activating/directing thiourea group. This method affords expedient access to structurally diverse enantioenriched, potentially bioactive alkenyl-containing aza-heterocycles and bicyclic aza-heterocycles.
Switchable Stereoselectivity in Bromoaminocyclization of Olefins: Using Br?nsted Acids of Anionic Chiral Cobalt(III) Complexes
Jiang, Hua-Jie,Liu, Kun,Yu, Jie,Zhang, Ling,Gong, Liu-Zhu
supporting information, p. 11931 - 11935 (2017/09/20)
Br?nsted acids of anionic chiral CoIII complexes act as bifunctional phase-transfer catalysts to shuttle the substrates across the solvent interface and control stereoselectivity. The diastereomeric chiral CoIII-templated Br?nsted ac
Reactivity of seven-membered azazirconacycloallenes and four-membered zirconacycles toward diphenylacetonitrile
Zhao, Jing,Zhang, Shaoguang,Zhang, Wen-Xiong,Xi, Zhenfeng
, p. 8370 - 8374 (2013/02/22)
The reaction of the seven-membered azazirconacycloallene 2 with Ph 2CHCN was carried out to yield a zirconocene complex with three fused rings and a keteniminate ligand. Further reactivity toward propargyl bromide or propionyl chloride shows that the keteniminate ligand can be replaced by halogen atoms (Br or Cl). In addition, the reaction of the strained four-membered zirconacycle 1 with Ph2CHCN gives zirconocenes possessing vinyl-imine and keteniminate species.