326595-91-9Relevant academic research and scientific papers
Asymmetric synthesis and determination of the absolute configuration of FK584, an agent for the treatment of overactive detrusor
Take,Okumura,Tsubaki,Taniguchi,Shiokawa
, p. 1903 - 1907 (2007/10/03)
FK584[(-)-N-tert-butyl-4,4-diphenyl-2-cyclopentenylamine hydrochloride, (-)-4·HCl], a potential candidate for the treatment of overactive detrusor, was synthesized in a 4-step approach starting with Sharpless oxidation of cyclopentenol 6 (kinetic resoluti
Agents for the treatment of overactive detrusor. V. Synthesis and inhibitory activity on detrusor contraction of N-tert-butyl-4,4-diphenyl-2- cyclopentenylamine
Take, Kazuhiko,Okumura, Kazuo,Tsubaki, Kazunori,Taniguchi, Kiyoshi,Terai, Takao,Shiokawa, Youichi
, p. 1858 - 1864 (2007/10/03)
N-tert-Butyl-4,4-diphenyl-2-cyclopentenylamine ((±)-3) was designed to restrict the conformation of terodiline I and was synthesized in a 6-step approach starting with diphenylacetaldehyde (10) or in a 4-step approach starting with 2,2-diphenyl-4-pentenoi
Substituted-amine compound and a process for the preparation thereof
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, (2008/06/13)
The compound (-)-N-t-butyl-4,4-diphenyl-2-cyclopentenylamine, or its hydrochloride salt has anticholinergic activity, and thus has a variety of pharmaceutical utilities.
