2160-52-3

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 5-bromo-4-nitrothiophene-2-carboxylate is utilized as a versatile building block for the synthesis of important compounds in the pharmaceutical industry. Its unique structure allows for the creation of biologically active substances and pharmaceuticals, contributing to the development of new drugs and therapies.
Used in Organic Chemistry:
In the field of organic chemistry, ethyl 5-bromo-4-nitrothiophene-2-carboxylate is employed as a reagent in the synthesis of novel molecules with potential medicinal properties. Its chemical properties enable the formation of new compounds that can be further explored for their therapeutic applications.
Used in Research and Development:
Ethyl 5-bromo-4-nitrothiophene-2-carboxylate is also used in research and development applications for the creation of new drug candidates and molecular probes. Its presence in various chemical reactions aids in the discovery of innovative compounds with potential applications in medicine and other fields.

Upstream product

• 5751-83-7 ethyl 5-bromothiophene-2-carboxylate 

Relevant academic research and scientific papers

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides

The discovery of a novel class of HCV NS5B polymerase inhibitors, 3-arylsulfonylamino-5-phenyl-thiophene-2-carboxylic acids is described. SAR studies have yielded several potent inhibitors of HCV polymerase as well as of HCV subgenomic RNA replication in

DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS

Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols according to formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme.

DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS

The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1 -phenyl-2-pyridinyl alkyl alcohols, methods of preparing such compounds, compositions containing them and therapeutic use thereof.