Bioorganic and Medicinal Chemistry Letters p. 793 - 796 (2004)
Update date:2022-08-30
Topics:
Chan, Laval
Das, Sanjoy K.
Reddy, T. Jagadeeswar
Poisson, Carl
Proulx, Melanie
Pereira, Oswy
Courchesne, Marc
Roy, Caroline
Wang, Wuyi
Siddiqui, Arshad
Yannopoulos, Constantin G.
Nguyen-Ba, Nghe
Labrecque, Denis
Bethell, Richard
Hamel, Martine
Courtemanche-Asselin, Philippe
L'Heureux, Lucille
David, Maud
Nicolas, Olivier
Brunette, Stephanie
Bilimoria, Darius
Bedard, Jean
The discovery of a novel class of HCV NS5B polymerase inhibitors, 3-arylsulfonylamino-5-phenyl-thiophene-2-carboxylic acids is described. SAR studies have yielded several potent inhibitors of HCV polymerase as well as of HCV subgenomic RNA replication in
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