21609-90-5 Usage
Uses
Used in Pharmaceutical Industry:
Leptomycin B is used as an antiviral agent for its ability to inhibit the nuclear export of HIV-1 regulatory protein Rev, which plays a crucial role in the virus's replication cycle. This action helps in controlling the spread of the virus and managing the infection.
Used in Insecticide Applications:
Leptomycin B is used as an insecticide, providing a means to control and eliminate insect pests. However, it is important to note that its use is not permitted in the United States due to potential environmental and health concerns.
Chemical Properties:
Leptomycin B is characterized by its white crystalline or colorless amorphous solid form, with the technical product appearing as a light tan powder. Its chemical properties contribute to its effectiveness in both pharmaceutical and insecticide applications.
Reactivity Profile
Organophosphates, such as LEPTOMYCIN B, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Health Hazard
LEPTOMYCIN B is highly toxic; it is capable of causing death or permanent injury by exposure during normal use.
Fire Hazard
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) Container may explode in heat of fire. Fire may produce irritating or poisonous gases. Decomposes above 356F. Avoid strong alkalies.
Potential Exposure
A potential danger to those involved
in the manufacture, formulation and application of this
insecticide. Its use is not currently permitted in the United
States of America
Shipping
UN2783 Organophosphorus pesticides, solid,
toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
UN3464 Organophosphorus compound, solid, toxic, n.o.s,
Hazard Class: 6.1; Labels: 6.1-Poisonous materials,
Technical Name Required
Incompatibilities
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, and epoxides. Organophosphates are
susceptible to formation of highly toxic and flammable
phosphine gas in the presence of strong reducing agents
such as hydrides and active metals. Partial oxidation by
oxidizing agents may result in the release of toxic phosphorus oxides.
Waste Disposal
Small amounts may be treated
with alkali then burned in a landfill. Large quantities
should be incinerated in a unit with effluent gas scrubbing. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticidecontainers. Must be disposed properly by following package label directions or by contacting your local or federal
environmental control agency, or by contacting your
regional EPA office
Check Digit Verification of cas no
The CAS Registry Mumber 21609-90-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,0 and 9 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 21609-90:
(7*2)+(6*1)+(5*6)+(4*0)+(3*9)+(2*9)+(1*0)=95
95 % 10 = 5
So 21609-90-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H10BrCl2O2PS/c1-17-19(20,9-5-3-2-4-6-9)18-13-8-11(15)10(14)7-12(13)16/h2-8H,1H3
21609-90-5Relevant academic research and scientific papers
Synthesis method and application of epoxy resin low-curing-shrinkage-rate expansion monomer
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Paragraph 0019-0021, (2020/05/02)
The invention discloses a synthesis method and application of an epoxy resin low-curing-shrinkage-rate expansion monomer. The synthesis method comprises the following steps: 1, synthesizing 3-cyclohexyl-1, 1-dimethanol, 2, carrying out transesterification on the 3-cyclohexyl-1, 1-dimethanol to synthesize normal orthocarbonate, and 3, carrying out an epoxidation reaction process on the normal orthocarbonate to synthesize the spiro-orthocarbonate expansion monomer containing the epoxy group. When the spiro-orthocarbonate expansion monomer containing the epoxy group is used for a curing reactionof an epoxy resin, the curing shrinkage rate of the epoxy resin can be effectively reduced.
4,4-BIS[(ETHENYLOXY)METHYL]CYCLOHEXENE AND METHOD FOR PRODUCING SAME
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Paragraph 0020; 0021; 0022; 0023; 0024, (2014/03/24)
A novel substance, 4,4-bis[(ethenyloxy)methyl]cyclohexene having the formula (I), which is low in odor, low in volatility, and low in skin irritability, and therefore, can be used as, for example, a starting material for inks and a starting material for electronic materials, and a method for producing the same are provided:
Synthesis of 4,4-disubstituted 2-aminocyclopentanecarboxylic acid derivatives and their incorporation into 12-helical β-peptides
Peelen, Timothy J.,Chi, Yonggui,English, Emily Payne,Gellman, Samuel H.
, p. 4411 - 4414 (2007/10/03)
(Chemical equation presented) An enantioselective synthetic route is reported for trans-2-aminocyclopentanecarboxylic acids (ACPC) bearing geminal side chain pairs at the 4-position. β-Peptides containing the 4,4-disubstituted ACPC residues adopt the 12-helical conformation, as demonstrated by 2D NMR analysis in aqueous solution. These 4,4-disubstituted ACPC residues display functional groups, including acidic and hydrogen bond donating groups, in a geometrically defined fashion, which should be useful for the design of β-peptides for specific applications.
Organotin-containing composition for the stabilization of polymers of vinyl chloride
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, (2008/06/13)
An organotin-containing composition for the stabilization of polymers or copolymers of vinyl chloride in which there is incorporated a stabilizing amount of an organotin compound containing at least two tin atoms and which is a mercapto, hydroxy or alkoxy substituted ester of a mercapto acid substituted organotin mercapto acid diester.
