21612-28-2

Upstream product

• 21612-27-1 N^α-(N-benzyloxycarbonyl-β-alanyl)-histidine methyl ester 
• 51513-97-4 N-[(phenylmethoxy)carbonyl]-β-alanine chloride 
• 17908-25-7 1,N^α-bis-trimethylsilanyl-histidine trimethylsilanyl ester 
• 1499-46-3 L-Histidine methyl ester 
• 54755-77-0 N-benzyloxycarbonyl-3-aminopropionic acid methyl ester 
• 2304-94-1 3-(benzyloxycarbonylamino)propanoic acid 
• 21855-66-3 benzyl N-[2-(hydrazinecarbonyl)ethyl]carbamate 
• 501-53-1 benzyl chloroformate 
• 305-84-0 Carnosine 

Downstream Products

• 5853-00-9 D-carnosine 
• 1318262-66-6 3-(benzyloxycarbonylamino)propionyl-L-histidine ethyl ester 
• 1313206-50-6 3-(benzyloxycarbonylamino)-N-[(1S)-2-hydroxy-1-(1H-imidazol-5-yl-methyl)ethyl]propanamide 
• 305-84-0 Carnosine 

Relevant academic research and scientific papers

METHOD FOR PRODUCING L-CARNOSINE DERIVATIVE AND L-CARNOSINE

PROBLEM TO BE SOLVED: To provide a convenient method for producing a high-purity N-protected L-carnosine derivative and L-carnosine. SOLUTION: A production method includes reacting an acid halide (1) with an L-histidine derivative (2). (R1 and R2 are H or a protection group of an amino group; X is a halogen atom). (A TMS group is a trimethylsilyl group). SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES

The present invention relates to amino alcohol derivatives of general formula (I). These derivatives possess an interesting activity in that they block the secondary products of lipid oxidative stress, and are consequently suitable for therapeutic use in