21613-46-7

Upstream product

• 3815-30-3 4-(4-methoxyphenyl)-3-buten-2-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 201932-61-8 (E)-β-(N-hydroxyimino)propyldiphenylphosphine oxide 

Downstream Products

• 4211-85-2 5-(4-methoxyphenyl)-3-methylisoxazole 
• 1357560-52-1 4-(4-methoxyphenyl)-6-methyl-2,3-dipropylpyridine 
• 70265-93-9 5-(4-methoxy-phenyl)-3-methyl-4,5-dihydro-isoxazol-4-ol 
• 185244-97-7 2-chloro-5-(4-methoxyphenyl)-nicotinaldehyde 
• 86069-28-5 (E)-4-(4-Methoxy-phenyl)-but-3-en-2-one O-(2-dimethylamino-1-methyl-ethyl)-oxime 
• 86069-30-9 (E)-4-(4-Methoxy-phenyl)-but-3-en-2-one O-(2-dimethylamino-propyl)-oxime 

Relevant academic research and scientific papers

Rhodium(III)-catalyzed synthesis of pyridines from α,β- unsaturated ketoximes and internal alkynes

A method for the synthesis of highly substituted pyri-dines from ,-unsaturated oximes and internal alkynes has been developed using [Cp*RhCl2]2-CsOPiv as the catalyst system. The present transformation is carried out by a redox-neutral sequence of vinylic C-H rhodation, alkyne insertion, and C-N bond formation of the putative vinyl rhodium intermediate with the oxime nitrogen, where the N-O bond of oxime derivatives could work as an internal oxidant to maintain the catalytic cycle. Georg Thieme Verlag Stuttgart · New York.

An improved and effective method for the preparation of α,β- unsaturated oximes and isoxazole derivatives

β-Functionalized oximes derived from phosphine oxides 5, phosphonates 8 and phosphonium salts 10 are easily obtained by simple addition of hydroxylamine compounds 2 to substituted allenes 3 and 6 or to propargylphosphonium salt 9. These oximo derivatives