216168-60-4Relevant academic research and scientific papers
PHENOLIC ANTIOXIDANTS FOR THE TREATMENT OF DISORDERS INCLUDING ARTHRITIS, ASTHMA AND CORONARY ARTERY DISEASE
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, (2010/02/14)
The invention relates to compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds, wherein the compounds are of the following Formulas: or a pharmaceutically acceptable salt, ester or prodrug thereof, wherein the
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases
Meng, Charles Q.,Somers, Patricia K.,Hoong, Lee K.,Zheng, X. Sharon,Ye, Zhihong,Worsencroft, Kimberly J.,Simpson, Jacob E.,Hotema, Martha R.,Weingarten, M. David,MacDonald, Mathew L.,Hill, Russell R.,Marino, Elaine M.,Suen, Ki-Ling,Luchoomun, Jayraz,Kunsch, Charles,Landers, Laura K.,Stefanopoulos, Dimitria,Howard, Randy B.,Sundell, Cynthia L.,Saxena, Uday,Wasserman, Martin A.,Sikorski, James A.
, p. 6420 - 6432 (2007/10/03)
Vascular cell adhesion molecule-1 (VCAM-1) mediates recruitment of leukocytes to endothelial cells and is implicated in many inflammatory conditions. Since part of the signal transduction pathway that regulates the activation of VCAM-1 expression is redox
