216174-17-3Relevant academic research and scientific papers
Rhodium(II) acetate-catalyzed reaction of 2-amino-4,5-dihydro-3-furancarbonitriles with α-diazo-β-keto esters
Yamagata, Kenji,Akizuki, Keiko,Yamazaki, Motoyoshi
experimental part, p. 627 - 631 (2011/10/19)
2-Amino-4,5-dihydro-3-furancarbonitriles (1) react with α-diazo-β-keto esters in the presence of rhodium (II) acetate to give alkyl 2H-pyran-2-carboxylates (2) in good yields. Benzoylation of 2 with benzoyl chloride provided alkyl 3-benzoylimino-2H-pyran-2-carboxylates (4). The formation of 2 could be explained by a mechanism involving an oxonium ylide derived from the rhodium carbenoids and 1.
