2162-75-6

Basic information

• Product Name: bis(2,6-diethylphenyl)cyanamide
• CAS NO: 2162-75-6
• Molecular Formula: C₂₁H₂₆N₂
• Molecular Weight: 306.4445
• Mol File: 2162-75-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 457.1°C at 760 mmHg
• Flash Point: 184.1°C
• Density: 1.026g/cm³
• Vapor Pressure: 1.53E-08mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: bis(2,6-diethylphenyl)cyanamide(CAS DataBase Reference)
• NIST Chemistry Reference: bis(2,6-diethylphenyl)cyanamide(2162-75-6)
• EPA Substance Registry System: bis(2,6-diethylphenyl)cyanamide(2162-75-6)

Safety Data

• Hazardous Substances Data: 2162-75-6(Hazardous Substances Data)

Usage

General Description

Bis(2,6-diethylphenyl)cyanamide is a chemical compound with the molecular formula C18H24N2. It is a cyanamide derivative with two 2,6-diethylphenyl groups attached to the nitrogen atom. bis(2,6-diethylphenyl)cyanamide is commonly used as a building block in organic synthesis and as a reagent in various chemical reactions. It has potential applications in pharmaceuticals and agrochemicals, as well as in the production of specialty chemicals and materials. Bis(2,6-diethylphenyl)cyanamide is a white to light yellow solid with a molecular weight of 272.39 g/mol, and it is important to handle it with care, as it can be harmful if ingested or inhaled and may cause irritation to the skin and eyes.

Upstream product

• 25348-96-3 1,3-bis(2,6-diethylphenyl)-thiourea 
• 20458-99-5 2,6-diethylphenylisocyanate 

Relevant articles and documents

Metal-free access of bulky: N, N ′-diarylcarbodiimides and their reduction: Bulky N, N ′-diarylformamidines

A metal-free synthesis of symmetrical and unsymmetrical bulky N,N′-diaryl carbodiimides from the dehydrosulfurisation of their corresponding N,N′-diarylthiourea with 4-dimethylaminopyridine (DMAP) and iodine under mild reaction conditions with moderate to excellent yields has been established. In the literature, the classical method of dehydrosulfurisation of bulky N,N′-diarylthiourea to N,N′-diarylcarbodiimide has been reported using toxic metal oxide (HgO) and magnesium sulphate (MgSO4) under harsh reaction conditions. Furthermore, easy access to 1,3-disubstituted symmetric and unsymmetrical N,N′-diaryl formamidines involving the reaction of symmetrical and unsymmetrical N,N′-diaryl carbodiimides with sodium borohydride is described. The widely used method for the preparation of bulky N,N′-diaryl formamidines is the treatment of primary amines with triethylorthoformate in the presence of acid under high temperature reaction conditions.