21627-60-1Relevant articles and documents
Riminophenazine derivatives as potential antituberculosis agents: Synthesis, biological, and electrochemical evaluations
Bvumbi, Mpelegeng Victoria,Mmutlane, Edwin M.,Ngwane, Andile,van der Westhuyzen, Chris
supporting information, (2021/07/26)
A series of novel riminophenazine derivatives, having ionizable alkyl substituents at N-5 and a variety of substituents on the C-3 imino nitrogen, at C-8 and on the pendant aryl group, have been designed and synthesized. Preliminary investigations into th
Indole RSK inhibitors. Part 2: Optimization of cell potency and kinase selectivity
Kirrane, Thomas M.,Boyer, Stephen J.,Burke, Jennifer,Guo, Xin,Snow, Roger J.,Soleymanzadeh, Lida,Swinamer, Alan,Zhang, Yunlong,Madwed, Jeffery B.,Kashem, Mohammed,Kugler, Stanley,O'Neill, Margaret M.
scheme or table, p. 738 - 742 (2012/03/11)
A series of inhibitors for the 90 kDa ribosomal S6 kinase (RSK) based on an 1-oxo-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,2-a]indole-8-carboxamide scaffold were optimized for cellular potency and kinase selectivity. This led to the identification of compound 24, BIX 02565, an attractive candidate for use in vitro and in vivo to explore the role of RSK as a target for the treatment heart failure.
Benzimidazole derivative, hair growth promoter and external composition for skin using the same
-
, (2008/06/13)
A benzimidazole derivative or a salt thereof expressed by the following Formula (I): wherein one of A and B is a hydrocarbon group of C10-30expressed by R1and the other is —(CH2)n—NR2R3; R
