21629-48-1 Usage
Uses
Used in Pharmaceutical Research:
7-Chloro-2,8-dimethyl-4-quinolinol is utilized as a key intermediate in the synthesis of various pharmaceutical compounds due to its unique structure and reactivity. Its potential pharmacological properties have been studied extensively, including its antibacterial, antifungal, and antiviral activities, which make it a promising candidate for drug development.
Used in Agrochemicals:
This chemical compound has also been investigated for its potential use in agrochemicals, where it can be employed as an active ingredient in the development of pesticides and other agricultural products. Its broad-spectrum activity against various pathogens can contribute to improved crop protection and yield.
Used in Analytical Chemistry as a Chelating Agent:
7-Chloro-2,8-dimethyl-4-quinolinol has been explored for its potential as a chelating agent in analytical chemistry. Its ability to form stable complexes with metal ions can be leveraged in various analytical techniques, such as spectrophotometry and chromatography, to enhance the selectivity and sensitivity of these methods.
Check Digit Verification of cas no
The CAS Registry Mumber 21629-48-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,2 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 21629-48:
(7*2)+(6*1)+(5*6)+(4*2)+(3*9)+(2*4)+(1*8)=101
101 % 10 = 1
So 21629-48-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H10ClNO/c1-6-5-10(14)8-3-4-9(12)7(2)11(8)13-6/h3-5H,1-2H3,(H,13,14)
21629-48-1Relevant academic research and scientific papers
N1-{4-[(10S)-Dihydroartemisinin-10-oxyl]}phenylmethylene-N 2-(2-methylquinoline-4-yl)hydrazine derivatives as antiplasmodial falcipain-2 inhibitors
Luo, Wei,Liu, Yang,Wang, Jian,Guo, Chun,Lu, Wei-Qiang,Cui, Kun-Qiang
, p. 3073 - 3079,7 (2020/08/20)
A series of N1-{4-[(10S)-dihydroartemisinin- 10-oxyl]}phenylmethylene-N2-(2-methylquinoline-4-yl) hydrazine derivatives 9a-9n possessing 4-quinolylhydrazone and artemisinin cores were herein synthesized and evaluated for their activities against cysteine protease falcipain- 2 of Plasmodium falciparum. The structures were clearly confirmed by elemental analysis, 1H NMR, and mass spectra. The pharmacological results indicated that all compounds showed excellent activity against recombinant falcipain-2 (IC50 = 0.15-2.28 μM). The best one of this series was compound 9d (IC50 = 0.15 μM). The molecular docking results showed that the compound 9d made close contact with the key active site of cysteine protease falcipain-2.
