216306-34-2Relevant academic research and scientific papers
Aluminum-controlled reactivity and diastereoselectivity toward radical reactions of optically active aldimines with metallic samarium
Yanada,Okaniwa,Kaieda,Ibuka,Takemoto
, p. 1283 - 1286 (2007/10/03)
The intermolecular pinacol-type coupling reaction and allylation reaction of optically active imines bearing a β-hydroxy group were performed stereoselectively with metallic samarium after treatment of the imines with trimethylaluminum.
High asymmetric induction in anionic amino-cope rearrangements controlled by β-aminoalcohol auxiliaries
Allin, Steven M.,Button, Martin A. C.,Baird, Robert D.
, p. 1117 - 1119 (2007/10/03)
Novel 3-amino-1,5-dienes were prepared with high diastereoselectivity by unprecedented 1,2-addition of allyl Grignard to α,β-unsaturated imines containing β-aminoalcohol auxiliaries. Asymmetric anionic amino-Cope rearrangement of the diastereoisomerically pure 3-amino-1,5-diene substrates proceeded to yield the target 3-substituted aldehyde in good yield and with high levels of asymmetric induction (up to 94% e.e.).
