216449-79-5

Downstream Products

• 216449-81-9 2,2,2-Trichloro-acetimidic acid (3S,4S)-5-(tert-butyl-diphenyl-silanyloxy)-3-hydroxy-4-methyl-2-methylene-pentyl ester 
• 216449-87-5 1-{4-[(1S,2S)-3-(tert-Butyl-diphenyl-silanyloxy)-1-methoxymethoxy-2-methyl-propyl]-2-trichloromethyl-4,5-dihydro-oxazol-4-ylmethoxy}-2,2,6,6-tetramethyl-piperidine 
• 216449-85-3 (1S,2S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-1-[4-(2,2,6,6-tetramethyl-piperidin-1-yloxymethyl)-2-trichloromethyl-4,5-dihydro-oxazol-4-yl]-propan-1-ol 

Relevant academic research and scientific papers

An enantiocontrolled synthesis of a key intermediate to (+)-lactacystin

An asymmetric synthesis of a key intermediate 16 to (+)-lactacystin 1 has been established starting from epoxide 2 via intramolecular mercurioamidation of allylic trichloroacetimidate 4 and concomitant addition-reduction of ester 13 by Pr(i) MgBr, in whic