216481-08-2

Upstream product

• 205648-24-4 (S)-6-(benzyloxy)methyl-2-{2-[1-(tert-butoxycarbonyl)aminoethyl]-5-methyloxazol-4-yl}-3-(4-ethoxycarbonylthiazol-2-yl)pyridine 
• 78981-25-6 tert-butyl (1S)-2-amino-1-methyl-2-oxoethylcarbamate 
• 205648-15-3 N-(tert-butoxycarbonyl)-N'-[2-(1-methoxycarbonyl-3-oxobutyl)]-S-alaninamide 
• 205648-17-5 (S)-2-[1-(tert-butoxycarbonyl)aminoethyl]-5-methyloxazole-4-carboxylic acid 
• 205648-16-4 (S)-methyl 2-(1-((tert-butoxycarbonyl)amino)ethyl)-5-methyloxazole-4-carboxylate 
• 205648-18-6 (S)-ethyl 3-{2-[1-(tert-butoxycarbonyl)aminoethyl]-5-methyloxazol-4-yl}-3-oxopropanoate 
• 205648-19-7 (S)-ethyl 3-amino-{2-[1-(tert-butoxycarbonyl)aminoethyl]-5-methyloxazol-4-yl}propenoate 
• 205648-22-2 (S)-6-(benzyloxy)methyl-2-{2-[1-(tert-butoxycarbonyl)aminoethyl]-5-methyloxazol-4-yl}pyridine-3-carboxamide 
• 205648-23-3 (S)-6-(benzyloxy)methyl-2-{2-[1-(tert-butoxycarbonyl)aminoethyl]-5-methyloxazol-4-yl}pyridine-3-thiocarboxamide 
• 205648-21-1 (S)-6-(benzyloxy)methyl-2-{2-[1-(tert-butoxycarbonyl)aminoethyl]-5-methyloxazol-4-yl}pyridine-3-carboxylic acid 
• 205648-20-0 (S)-ethyl 6-(benzyloxy)methyl-2-{2-[1-(tert-butoxycarbonyl)aminoethyl]-5-methyloxazol-4-yl}pyridine-3-carboxylate 

Downstream Products

• 216481-00-4 C₄₀H₄₁N₉O₇S₂ 
• 271597-68-3 2-({(S)-2-[(2-{6-Benzyloxymethyl-2-[2-((S)-1-tert-butoxycarbonylamino-ethyl)-5-methyl-oxazol-4-yl]-pyridin-3-yl}-thiazole-4-carbonyl)-amino]-3-methyl-butyrylamino}-methyl)-5-methyl-oxazole-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of the thiopeptide promothiocin A

The thiopeptide (or thiostrepton) antibiotics are a class of sulfur-containing highly modified cyclic peptides with interesting biological activity. Described herein is the total synthesis of the thiopeptide antibiotic promothiocin A, which utilizes a mod

The first synthesis of promothiocin A

The first total synthesis of the naturally occurring macrocyclic thiopeptide promothiocin A 1 is described.