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4,4-DIFLUORO-1,3,5,7-TETRAMETHYL-4-BORA-3A,4A-DIAZA-S-INDACENE, also known as BODIPY, is a class of fluorescent dyes derived from boron-dipyrromethene. It exhibits unique photophysical properties, such as high quantum yields, large molar absorptivities, and photostability. These characteristics make it a versatile and promising candidate for various applications in different fields.

21658-70-8

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21658-70-8 Usage

Uses

Used in Biochemical Research:
4,4-DIFLUORO-1,3,5,7-TETRAMETHYL-4-BORA-3A,4A-DIAZA-S-INDACENE is used as a fluorescent probe for generating fluorescent conjugates of proteins, nucleotides, oligonucleotides, and dextrans. It aids in the study of biomolecular interactions, cellular processes, and intracellular dynamics.
Used in Enzyme Assays:
In the field of enzymology, 4,4-DIFLUORO-1,3,5,7-TETRAMETHYL-4-BORA-3A,4A-DIAZA-S-INDACENE is used as a fluorescent enzyme substrate. It enables the monitoring of enzyme activity and the development of assays for various enzymes.
Used in Analytical Chemistry:
4,4-DIFLUORO-1,3,5,7-TETRAMETHYL-4-BORA-3A,4A-DIAZA-S-INDACENE is used as a fluorescent indicator for detecting and quantifying fatty acids, phospholipids, lipopolysaccharides, and other analytes. Its sensitivity and selectivity make it a valuable tool in analytical chemistry.
Used in Drug Discovery:
In the pharmaceutical industry, 4,4-DIFLUORO-1,3,5,7-TETRAMETHYL-4-BORA-3A,4A-DIAZA-S-INDACENE is used as a fluorescent tag for receptor ligands. It helps in the identification and characterization of potential drug candidates and their interactions with target receptors.
Used in Materials Science:
4,4-DIFLUORO-1,3,5,7-TETRAMETHYL-4-BORA-3A,4A-DIAZA-S-INDACENE is used as a fluorescent component in the preparation of polystyrene microspheres and other materials. It contributes to the development of advanced materials with unique optical properties and potential applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 21658-70-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,5 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 21658-70:
(7*2)+(6*1)+(5*6)+(4*5)+(3*8)+(2*7)+(1*0)=108
108 % 10 = 8
So 21658-70-8 is a valid CAS Registry Number.

21658-70-8Relevant academic research and scientific papers

Synthesis and photo-physical properties of a series of BODIPY dyes

Banfi, Stefano,Nasini, Gianluca,Zaza, Stefano,Caruso, Enrico

, p. 4845 - 4856 (2013/07/04)

A series of 39 boron-dipyrrolylmethenes (BODIPYs) have been synthesized and characterized. Their spectroscopic properties, degree of lipophilicity, chemical stability under irradiation, and singlet-oxygen generation rate have also been studied. These compounds differ in the presence of ethyl groups (group A), hydrogens (group B) or iodines (group C) on the 2,6 positions; these appendices confer particular characteristics to each group. The presence of an aromatic substituent or hydrogen on the indacene 8 position produces 13 different molecules of each group. Besides the effects exerted by the group or atom on the 2,6 positions, the substituent on the 8 position exerts a further effect on the physico-chemical parameters, thus the desired properties of BODIPYs, concerning fluorescence, lipophilicity, and singlet oxygen production can be modulated accordingly.

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