2166-12-3

Upstream product

• 6273-45-6 4-(4-chlorophenyl)-4-oxo-2-phenylbutanenitrile 
• 6273-34-3 methyl 4-oxo-4-(4-chlorophenyl)-2-phenyl-butanoate 
• 116776-52-4 4-(4-chloro-phenyl)-4-oxo-2-phenyl-butyric acid 

Downstream Products

• 116776-67-1 4-[6-(4-Chloro-phenyl)-4-phenyl-pyridazin-3-yl]-morpholine 
• 116776-70-6 6-(4-Chloro-phenyl)-4-phenyl-3-piperidin-1-yl-pyridazine 
• 116776-64-8 [6-(4-Chloro-phenyl)-4-phenyl-pyridazin-3-yl]-dimethyl-amine 
• 116776-62-6 3-Chloro-6-(4-chloro-phenyl)-4-phenyl-pyridazine 
• 75616-30-7 6-(4-Chloro-phenyl)-4-phenyl-2H-pyridazin-3-one 
• 76617-86-2 6-(4-Chloro-phenyl)-4,6-diphenyl-tetrahydro-pyridazin-3-one 

Relevant academic research and scientific papers

Microwave assisted synthesis of 4,6-diarylpyridazin-3(2H)-ones in solid state

Microwave assisted synthesis of dihydropyridazin-3(2H)-ones and the subsequent dehydrogenation using selenium dioxide are described.

A New Synthetic Route to 4,6-Diarylpyridazinones and Some of their Derivatives

A novel approach to the titled ring system starting from conveniently available chalcones 1 is proposed.It involves a catalysed exchange of hydrogen cyanide between acetone cyanohydrin and 1.The resulting γ-ketonitriles 2 give the expected 4,6-diarylpyrid