216699-35-3

Basic information

• Product Name: 5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*
• Synonyms: 5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*;5-carboxy-X-rhodaMine, triethylaMMoniuM salt;5-ROX, CXR;5-ROX, 5-CXR;9-(2,4-Dicarboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium inner salt;5-ROX [5-Carboxy-X-rhodaMine];1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium,9-(2,4-dicarboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-, inner salt;5-ROX [5-Carboxy-X-rhodamine] *CAS 216699-35-3*
• CAS NO: 216699-35-3
• Molecular Formula: C₃₃H₃₀N₂O₅
• Molecular Weight: 669.302
• Mol File: 216699-35-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*(216699-35-3)
• EPA Substance Registry System: 5-CARBOXY-X-RHODAMINE TRIETHYLAMINE SALT, FOR FLUORESCENCE*(216699-35-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• Hazardous Substances Data: 216699-35-3(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 216699-35-3 differently. You can refer to the following data:
1. 5-ROX is the purified isomer of 5(6)-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties
2. 5-ROX is a purified isomer of carboxy-X-rhodamine. 5-ROX is widely used for oligonucleotide labeling and automated DNA sequencing applications.

Definition

ChEBI: An X-rhodamine triethylammonium salt having a carboxy substituent at the 5-position.

Upstream product

• 536-90-3 m-Anisidine 
• 41175-50-2 8-hydroxyjulolidine 
• 552-30-7 trimellitic Anhydride 

Downstream Products

• 209734-74-7 5-carboxy-X-rhodamine N-succinimidyl ester 

Relevant articles and documents

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A compound, a method of imaging a cell, and a method of detecting a cancer, an inflammatory disease, or a neoplastic disease are provided. The compound includes a nitroxide derivative of a fluorophore that is activatable upon exposure to free radicals. The method of imaging a cell includes contacting the cell with an activatable nitroxide derivative of a fluorophore. The method of detecting a cancer, an inflammatory disease, or a neoplastic disease includes administering an activatable nitroxide derivative of a fluorophore and then imaging one or more cells contacted with the compound.

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