5-carboxy-X-rhodamine

Base Information

Chemical Name:5-carboxy-X-rhodamine
CAS No.:216699-35-3
Molecular Formula:C33H30 N2 O5
Molecular Weight:534.612
Hs Code.:
European Community (EC) Number:683-410-8
DSSTox Substance ID:DTXSID701314908
Wikidata:Q27122698
Mol file:216699-35-3.mol

Synonyms:5-carboxy-X-rhodamine

Suppliers and Price of 5-carboxy-X-rhodamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-ROX
10mg
$ 110.00

TCI Chemical
5-Carboxy-X-rhodamine
10MG
$ 125.00

TCI Chemical
5-Carboxy-X-rhodamine
50MG
$ 411.00

Labseeker
5-carboxy-X-rhodamine 95
5g
$ 4968.00

Crysdot
5-ROX 97%
50mg
$ 280.00

Crysdot
5-ROX 97%
5mg
$ 56.00

Crysdot
5-ROX 97%
10mg
$ 91.00

ChemPep
5-ROX ≥95%
500mg
$ 1250.00

Biosynth Carbosynth
5-Carboxy-X-rhodamine
10 mg
$ 103.00

Biosynth Carbosynth
5-Carboxy-X-rhodamine
5 mg
$ 65.00

Total 26 raw suppliers

Chemical Property of 5-carboxy-X-rhodamine

Chemical Property:

PSA：97.05000
LogP:5.12340
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:534.21547206
Heavy Atom Count:40
Complexity:1200

Purity/Quality:

99%, ^*data from raw suppliers

5-ROX ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=CC3=C(C4=C2N(C1)CCC4)OC5=C6CCC[N+]7=C6C(=CC5=C3C8=C(C=C(C=C8)C(=O)[O-])C(=O)O)CCC7
Uses 5-ROX is the purified isomer of 5(6)-ROX. It is preferred for some complicated biological applications where reproducibility is really critical. The minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties 5-ROX is a purified isomer of carboxy-X-rhodamine. 5-ROX is widely used for oligonucleotide labeling and automated DNA sequencing applications.

Technology Process of 5-carboxy-X-rhodamine

There total 3 articles about 5-carboxy-X-rhodamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 41175-50-2
8-hydroxyjulolidine

: 5-carboxyphthalaldehydic acid

: 216699-35-3
5-carboxy-X-rhodamine

Guidance literature:: With oxygen; In 2,2,2-trifluoroethanol; at 75 ℃; for 21h; regioselective reaction;
DOI:10.1021/acs.orglett.6b02635

Reference yield: 34.0%

: 41175-50-2
8-hydroxyjulolidine

: 552-30-7,145253-53-8
trimellitic Anhydride

: 194785-18-7
6-carboxy-X-rhodamine

: 216699-35-3
5-carboxy-X-rhodamine

Guidance literature:: With sulfuric acid; In n-PrCO₂H; for 12h; Reflux;
DOI:10.1021/ol801904k

Reference yield:

: 536-90-3,918666-97-4
m-Anisidine

: 216699-35-3
5-carboxy-X-rhodamine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / 19 h / 70 - 150 °C

2: pyridine hydrochloride / 2 h / 200 °C

3: toluene-4-sulfonic acid / propionic acid / 24 h / Reflux

With pyridine hydrochloride; sodium carbonate; toluene-4-sulfonic acid; In propionic acid;