216769-41-4Relevant articles and documents
Stereospecific ring expansion of chiral vinyl aziridines
Brichacek, Matthew,Navarro Villalobos, Mauricio,Plichta, Alexandra,Njardarson, Jon T.
, p. 1110 - 1113 (2011/04/25)
In this report, it is demonstrated that chiral vinyl aziridines can be stereospecifically ring expanded. This synthetic approach allows controlled access to chiral 2,5-cis-or 2,5-trans-3-pyrroline products from starting materials with the appropriate aziridine geometry. Twenty three ring expansion examples, most of which feature a stereospecific cyclization, are presented.(Figure Presented)
Stereoselective synthesis of oxazoline derivative
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, (2008/06/13)
The present invention relates to stereoselective synthetic method of oxazoline derivative. More particularly, it relates to a synthetic method of oxazoline derivative having the structure of formula I. wherein R represents phenyl, benzyl, methyl, ethyl, i
A highly stereocontrolled asymmetric synthesis of the Taxol C-13 side chain; (4S, 5R)-2,4-Diphenyloxazoline-5 carboxylic acid
Lee, Kee-Young,Kim, Yong-Hyun,Park, Min-Sung,Ham, Won-Hun
, p. 8129 - 8132 (2007/10/03)
A stereoselective synthesis of (4S, 5R)-2,4-diphenyloxaline-5-carboxylic acid, a precursor of the Taxol C-13 side chain was achieved using palladium- catalyzed oxazoline formation reaction from commercially available amino acid.
