216854-53-4

Basic information

• Product Name: 1-Allyl-1.2-diformyl hydrazine
• Synonyms: 1-Allyl-1.2-diformyl hydrazine;1-(2-Propen-1-yl)-1,2-hydrazinedicarboxaldehyde;1-(2-Propenyl)-1,2-hydrazinedicarboxaldehyde
• CAS NO: 216854-53-4
• Molecular Formula: C5H8N2O2
• Molecular Weight: 128.12922
• Mol File: 216854-53-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 191℃
• Flash Point: 70℃
• Appearance: /
• Density: 1.096
• PKA: 12.05±0.46(Predicted)
• CAS DataBase Reference: 1-Allyl-1.2-diformyl hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Allyl-1.2-diformyl hydrazine(216854-53-4)
• EPA Substance Registry System: 1-Allyl-1.2-diformyl hydrazine(216854-53-4)

Safety Data

• Hazardous Substances Data: 216854-53-4(Hazardous Substances Data)

Usage

Chemical Family

Belongs to the hydrazine family

Molecular Weight

128.13 g/mol

Usage

Used in the synthesis of various organic compounds, and as a starting material in the preparation of pharmaceuticals and agrochemicals

Physical State

Colorless to pale yellow liquid

Odor

Strong, pungent

Flammability

Flammable

Toxicity

May be toxic if ingested or inhaled

Synonyms

1,2-bis(1-allylformyl)hydrazine, 1,2-Bis(allylformyl)hydrazine

Upstream product

• 64-18-6 formic acid 

Downstream Products

• 216854-55-6 4-(acetylthio)-1,2-diformylpyrazolidine 
• 162887-23-2 4-bromo-1,2-diformylpyrazolidine 
• 216854-54-5 1-(2,3-dibromopropyl)-1,2-diformylhydrazine 

Relevant articles and documents

New straightforward synthesis and characterization of a unique 1β- methylcarbapenem antibiotic biapenem bearing a σ-symmetric bicyclotriazoliumthio group as the pendant moiety

Biapenem 1, (1R,5S,6S,)-2-[(6,7-dihydro-5H-pyrazolo[1,2- α][1,2,4]triazolium-6-yl)thio]-6-yl)thio]-6-[(R)-1-hydroxyethyl]-1- methylcarbapen-2-em-3-carboxylate, is a new non-natural 1β-methylcarbapenem antibiotic which exhibits a wide range of antibacterial activity, remarkable chemical stability, and extensive stability against human renal dehydropeptidase-I. Mercaptobicyclotriazolium chloride 2 useful for the pendant moiety of 1 was successfully synthesized starting from hydrazine hydrate 3 along an economically available synthetic route. The thiol 2 was efficiently exploited for an expeditious synthesis of biapenem 1. Characterization (crystal structure, nonbonded S- - -O interaction, conformational analysis, and CH- - -O hydrogen bonds) of 1 was investigated by its X-ray crystallographic, 1H NMR, and deuteration experiment analyses.