216856-80-3 Usage
Uses
Used in Pharmaceutical Industry:
1H-Carbazole, 6-chloro-2,3,4,4a,9,9a-hexahydrois used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique molecular structure and reactivity make it a promising candidate for the development of new drugs with potential therapeutic applications.
Used in Research:
This carbazole derivative is utilized in research settings to study the properties and reactions of heterocyclic compounds. Its chloro and hexahydrogroups provide a basis for investigating the effects of structural modifications on the compound's behavior and potential applications.
Used in Chemical Synthesis:
1H-Carbazole, 6-chloro-2,3,4,4a,9,9a-hexahydroserves as a key component in the synthesis of complex organic compounds. Its presence can influence the outcome of chemical reactions, enabling the production of novel compounds with specific properties and uses.
Check Digit Verification of cas no
The CAS Registry Mumber 216856-80-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,6,8,5 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 216856-80:
(8*2)+(7*1)+(6*6)+(5*8)+(4*5)+(3*6)+(2*8)+(1*0)=153
153 % 10 = 3
So 216856-80-3 is a valid CAS Registry Number.
216856-80-3Relevant academic research and scientific papers
Asymmetric Hydrogenation of Unprotected Indoles Catalyzed by η6-Arene/N-Me-sulfonyldiamine-Ru(II) Complexes
Touge, Taichiro,Arai, Takayoshi
supporting information, p. 11299 - 11305 (2016/10/12)
Protecting-group-free transformation is a challenging and important issue in atom-economical organic synthesis. The η6-arene/N-Me-sulfonyldiamine-Ru(II)-BF4 complex-catalyzed asymmetric hydrogenation of 2-substituted unprotected indoles in weakly acidic hexafluoroisopropanol gives optically active indoline compounds with up to >99% ee. Under mild reaction media, halogen atoms and synthetically important protecting groups (e.g., silyl ether, acetal, benzyl ether, and ester) on indoles are maintained, which is advantageous for the synthesis of further complex indoline molecules.