216872-48-9

Upstream product

• 100-52-7 benzaldehyde 
• 216872-31-0 5-O-benzyl-2,3-O-isopropylidene-L-gulono-1,4-lactone 
• 94840-08-1 2,3-O-isopropylidene-L-gulono-γ-lactone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 216872-43-4 3,5-O-benzylidene-L-gulono-1,4-lactone 

Downstream Products

• 874350-68-2 C₁₉H₂₇N₃O₅Si 
• 216872-53-6 3,5-O-benzylidene-6-O-t-butyldimethylsilyl-L-xylo-hex-2-ulosonic acid 1,4-lactone 2-hydrate 

Relevant academic research and scientific papers

SYNTHESIS OF POLYHYDROXYLATED ALKALOIDS

A process for the production of a polyhydroxylated bicyclic (e.g. pyrrolizidine such as casuarine (10), indolizidine or quinolizidine) alkaloid comprises the cyclisation of a pyrrolidine or piperidine intermediate having three or more free hydroxyl groups

Cis-1,2-Dihydrocatechols in chemical synthesis: First synthesis of L-ascorbic acid (vitamin C) from a non-carbohydrate source

The cis-1,2-dihydrocatechol (2), which is obtained in enantiopure form by microbial oxidation of chlorobenzene, has been converted, via 3,5-O-benzylidene-L-gulono-1,4-lactone (8), into L-ascorbic acid (1).

First synthesis of L-ascorbic acid (vitamin C) from a non-carbohydrate source

The enantiopure cis-1,2-dihydrocatechol 2, which is obtained by microbial oxidation of chlorobenzene, has been converted, via 3,5-O-benzylidene-L-gulonolactone (8), into L-ascorbic acid (1).