21696-06-0 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
Explanation
The compound is derived from benzene and carboxamide, which are its parent compounds.
Explanation
The compound has two imidazole groups attached to a central benzene ring, which is connected to a methylbenzene-1,4-dicarboxamide backbone.
Explanation
The compound is used in the manufacturing of various polymers and polymer blends to improve their processing, as well as in the rubber and plastics industries as a coupling agent and an adhesion promoter.
Explanation
The compound may pose health and safety hazards if not handled properly, emphasizing the need for careful handling and safety precautions.
Explanation
These are alternative names for the compound, which can be used interchangeably to refer to the same chemical.
Derivative of
Benzene and carboxamide
Structural features
Two imidazole groups and a methylbenzene-1,4-dicarboxamide backbone
Usage
Polymer processing aid, coupling agent, and adhesion promoter
Health and safety hazards
Potential risks when mishandled
Check Digit Verification of cas no
The CAS Registry Mumber 21696-06-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,9 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 21696-06:
(7*2)+(6*1)+(5*6)+(4*9)+(3*6)+(2*0)+(1*6)=110
110 % 10 = 0
So 21696-06-0 is a valid CAS Registry Number.
21696-06-0Relevant academic research and scientific papers
Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli
Haynes, Keith M.,Abdali, Narges,Jhawar, Varsha,Zgurskaya, Helen I.,Parks, Jerry M.,Green, Adam T.,Baudry, Jerome,Rybenkov, Valentin V.,Smith, Jeremy C.,Walker, John K.
, p. 6205 - 6219 (2017/08/02)
In Gram-negative bacteria, efflux pumps are able to prevent effective cellular concentrations from being achieved for a number of antibiotics. Small molecule adjuvants that act as efflux pump inhibitors (EPIs) have the potential to reinvigorate existing antibiotics that are currently ineffective due to efflux mechanisms. Through a combination of rigorous experimental screening and in silico virtual screening, we recently identified novel classes of EPIs that interact with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli. Herein, we present initial optimization efforts and structure-activity relationships around one of those previously described hits, NSC 60339 (1). From these efforts we identified two compounds, SLUPP-225 (17h) and SLUPP-417 (17o), which demonstrate favorable properties as potential EPIs in E. coli cells including the ability to penetrate the outer membrane, improved inhibition of efflux relative to 1, and potentiation of the activity of novobiocin and erythromycin.
