216978-35-7

Upstream product

• 52385-60-1 (3-methyl-2-methylethenyl)-2-buten-1-ol 
• 99978-27-5 2-(α-hydroxy-isopropyl)-3-methyl-crotonic acid ethyl ester 
• 100144-50-1 2-isopropenyl-3-methyl-crotonic acid methyl ester 
• 4412-05-9 2-isopropenyl-3-methyl-crotonic acid 
• 35044-52-1 ethyl 2-acetyl-3-methylbut-2-enoate 
• 144066-82-0 Acetic acid 2-isopropenyl-3-methyl-but-2-enyl ester 
• 144067-40-3 Acetic acid 5-formyl-2,6,6-trimethyl-cyclohex-1-enylmethyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 216978-34-6 1-Acetoxymethyl-5-hydroxymethyl-2,6,6-trimethylcyclohex-1-ene 

Downstream Products

• 216978-37-9 5-tert-Butyldimethylsilyloxymethyl-1-(6-tert-butyldiphenylsilyloxy-1-methoxy-3-methylenehexyl)-2,6,6-trimethylcyclohex-1-ene 
• 216978-36-8 1-[5-(tert-Butyl-dimethyl-silanyloxymethyl)-2,6,6-trimethyl-cyclohex-1-enyl]-6-(tert-butyl-diphenyl-silanyloxy)-3-methylene-hexan-1-ol 
• 216978-42-6 1-{3-[6-(tert-Butyl-diphenyl-silanyloxy)-1-methoxy-3-methylene-hexyl]-2,2,4-trimethyl-cyclohex-3-enyl}-propynone 
• 216978-41-5 1-{3-[6-(tert-Butyl-diphenyl-silanyloxy)-1-methoxy-3-methylene-hexyl]-2,2,4-trimethyl-cyclohex-3-enyl}-prop-2-yn-1-ol 
• 216978-39-1 1-{3-[6-(tert-Butyl-diphenyl-silanyloxy)-1-methoxy-3-methylene-hexyl]-2,2,4-trimethyl-cyclohex-3-enyl}-prop-2-en-1-ol 
• 216978-40-4 1-{3-[6-(tert-Butyl-diphenyl-silanyloxy)-1-methoxy-3-methylene-hexyl]-2,2,4-trimethyl-cyclohex-3-enyl}-propenone 
• 216978-38-0 3-[6-(tert-Butyl-diphenyl-silanyloxy)-1-methoxy-3-methylene-hexyl]-2,2,4-trimethyl-cyclohex-3-enecarbaldehyde 
• 216978-64-2 {3-[6-(tert-Butyl-diphenyl-silanyloxy)-1-methoxy-3-methylene-hexyl]-2,2,4-trimethyl-cyclohex-3-enyl}-methanol 
• 216978-66-4 Toluene-4-sulfonic acid 6-(5-acryloyl-2,6,6-trimethyl-cyclohex-1-enyl)-6-methoxy-4-methylene-hexyl ester 
• 216978-67-5 1-(6-Hydroxy-1-methoxy-3-methylenehexyl)-5-(1-oxoprop-2-ynyl)-2,6,6-trimethylcyclohex-1-ene 
• 216978-28-8 1-(6-Iodo-1-methoxy-3-methylenehexyl)-5-(1-oxoprop-2-ynyl)-2,6,6-trimethylcyclohex-1-ene 
• 216978-27-7 1-(6-Iodo-1-methoxy-3-methylenehexyl)-5-(1-oxoprop-2-enyl)-2,6,6-trimethylcyclohex-1-ene 
• 216978-65-3 1-(6-Hydroxy-1-methoxy-3-methylenehexyl)-5-(1-oxoprop-2-enyl)-2,6,6-trimethylcyclohex-1-ene 
• 174788-18-2 5-(tert-Butyl-dimethyl-silanyloxymethyl)-2,6,6-trimethyl-cyclohex-1-enecarbaldehyde 

Relevant academic research and scientific papers

The unexpected formation of bicyclo[2.2.1]heptane derivatives by Lewis acid-catalyzed transannular double cyclization

Attempted synthesis of the cyclooctanoid skeleton of taxane molecules, by an intramolecular Lewis acid catalyzed Hosomi-Sakurai cyclization of the allylsilane with the aldehyde moiety in 17, unexpectedly led to the formation of bicyclo[2.2.1]-heptane deri

A tandem radical macrocyclisation-transannular cyclisation approach towards the taxanes

Separate treatment of the iodotrienedione 19 and the iododienynedione 38 with Bu3SnH-AIBN produces the corresponding taxane ring systems 25 (25-30%) and 56 (50-60%) respectively by way of tandem radical macrocyclisation-radical transannular cyc