216985-67-0

Usage

Uses

Used in Pharmaceutical Industry:
[(3-CHLORO-BENZO[B]THIOPHENE-2-CARBONYL)-AMINO]-ACETIC ACID is used as a building block for the synthesis of various pharmaceutical compounds due to its unique structural features and potential biological activities. Its chemical properties allow for the creation of new drugs with improved efficacy and selectivity.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, [(3-CHLORO-BENZO[B]THIOPHENE-2-CARBONYL)-AMINO]-ACETIC ACID serves as a valuable molecule for the development of novel therapeutic agents. Its structural characteristics can be exploited to design drugs targeting specific biological pathways or receptors, potentially leading to more effective treatments for various diseases.
Used in Drug Discovery and Design:
[(3-CHLORO-BENZO[B]THIOPHENE-2-CARBONYL)-AMINO]-ACETIC ACID is utilized as a key component in drug discovery and design processes. Its unique chemical properties and potential pharmacological activities make it an attractive candidate for the development of innovative drugs with improved therapeutic profiles.

Upstream product

• 21815-91-8 3-chlorobenzo[b]thiophen-2-carbonyl chloride 
• 56-40-6 glycine 

Downstream Products

• 1352051-73-0 3-(3-chloro-1-benzo[b]thiophen-2-yl)-5-(4-methoxybenzylidene)-2-phenyl-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-74-1 3-(3-chloro-1-benzo[b]thiophen-2-yl)-5-(4-nitrobenzylidene)-2-phenyl-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-75-2 3-(3-chloro-1-benzo[b]thiophen-2-yl)-5-(4-chlorobenzylidene)-2-phenyl-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-76-3 5-benzylidene-3-(3-chloro-1-benzo[b]thiophen-2-yl)-2-(4-fluorophenyl)-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-77-4 3-(3-chlorobenzo[b]thiophen-2-yl)-2-(4-fluorophenyl)-5-(4-methoxybenzylidene)-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-78-5 3-(3-chlorobenzo[b]thiophen-2-yl)-2-(4-fluorophenyl)-5-(4-nitrobenzylidene)-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-80-9 3-(3-chlorobenzo[b]thiophen-2-yl)-5-(4-chlorobenzylidene)-2-(4-fluorophenyl)-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-81-0 1-acetyl-5-benzylidene-3-(3-chloro-1-benzo[b]thiophen-2-yl)-2-phenyl-1,2-dihydro-1,2,4-tri-azin-6(5H)-one 
• 1352051-82-1 1-acetyl-3-(3-chloro-1-benzothiophen-2-yl)-5-(4-methoxybenzylidene)-2-phenyl-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-83-2 1-acetyl-3-(3-chloro-1-benzothiophen-2-yl)-5-(4-nitrobenzylidene)-2-phenyl-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-84-3 1-acetyl-3-(3-chloro-1-benzothiophen-2-yl)-5-(4-chlorobenzylidene)-2-phenyl-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-85-4 1-acetyl-5-benzylidene-3-(3-chloro-1-benzothiophen-2-yl)-2-(4-fluorophenyl)-1,2-dihydro-1,2,4-triazin-6(5H)-one 
• 1352051-86-5 1-acetyl-3-(3-chlorobenzo[b]thiophen-2-yl)-2-(4-fluorophenyl)-5-(4-methoxybenzylidene)-1,2-dihydro-1,2,4-tri-azin-6(5H)-one 
• 1352051-87-6 1-acetyl-3-(3-chlorobenzo[b]thiophen-2-yl)-2-(4-fluoro-phenyl)-5-(4-nitrobenzylidene)-1,2-dihydro-1,2,4-triazin-6(5H)-one 

Relevant academic research and scientific papers

Synthesis and antimicrobial activity of oxazolone, imidazolone and triazine derivatives containing benzothiophene

3-Chloro-1-benzothiophene-2-carbonylchloride (1) was allowed to react with glycine to give 3-chloro-1-benzothiophen-2-yl-carbonylaminoacetic acid (2). Various aldehydes were treated with compound (2) in acetic anhydride to get 1,3-oxazol-5-ones (3a-d). Th

Synthesis and antimicrobial activity of oxazolone, imidazolone and triazine derivatives containing benzothiophene

3-Chloro-1-benzothiophene-2-carbonyl chloride 1 was reacted with glycine in acetone to give 3-chloro-1- benzothiophen-2-yl-carbonylaminoacetic acid 2. Various aldehydes on treatment with compound 2 in acetic anhydride to gave 1,3-oxazol-5-ones