21713-56-4

Basic information

• Product Name: Phosphinic acid, diphenyl-, 4-acetylphenyl ester
• CAS NO: 21713-56-4
• Molecular Formula: C20H17O3P
• Molecular Weight: 336.327
• Mol File: 21713-56-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Phosphinic acid, diphenyl-, 4-acetylphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphinic acid, diphenyl-, 4-acetylphenyl ester(21713-56-4)
• EPA Substance Registry System: Phosphinic acid, diphenyl-, 4-acetylphenyl ester(21713-56-4)

Safety Data

• Hazardous Substances Data: 21713-56-4(Hazardous Substances Data)

Upstream product

• 99-93-4 4-Hydroxyacetophenone 
• 1499-21-4 Diphenylphosphinic chloride 
• 829-85-6 diphenylphosphane 
• 4559-70-0 Diphenylphosphine oxide 
• 1079-66-9 chloro-diphenylphosphine 
• 1707-03-5 diphenyl-phosphinic acid 
• 261172-44-5 4-acetylphenoxide 
• 10259-20-8 4-nitrophenyl diphenylphosphinate 

Downstream Products

• 261172-44-5 4-acetylphenoxide 
• 102817-54-9 4-cyanophenyl diphenylphosphinate 
• 21713-55-3 O-4-chlorophenyl diphenylphosphinate 
• 1706-96-3 phenyl diphenylphosphinate 
• 21713-53-1 4-methyl-o-phenyl phenyl(phenyl)phosphinate 
• 1707-03-5 diphenyl-phosphinic acid 
• 1733-55-7 ethyl diphenylphosphinate 
• 6230-68-8 diphenyl(piperidin-1-yl)phosphine oxide 

Relevant articles and documents

Electrochemical Enabled Cascade Phosphorylation of N?H/O?H/S?H Bonds with P?H Compounds: An Efficient Access to P(O)-X Bonds

An electrochemical three component cascade phosphorylation reaction of various heteroatoms-containing nucleophiles including carbazoles, indoles, phenols, alcohols, and thiols with Ph2PH has been established. Electricity is used as the “traceless” oxidant and water and air are utilized as the “green” oxygen source. All kinds of structurally diverse organophosphorus compounds with P(O)-N/P(O)-O/P(O)-S bonds are assembled in moderate to excellent yields (three categories of phosphorylation products, 50 examples, up to 97 % yield). A tentative free radical course is put forward to rationalize the reaction procedure.

The α-effect in nucleophilic substitution reactions of Y-substituted-phenyl diphenylphosphinates with HOO- and OH -

Second-order rate constants (kHOO-) for the nucleophilic substitution reactions of Y-substituted-phenyl diphenylphosphinates (4a-4i) with HOO- in H2O have been measured spectrophotometrically. The a-nucleophile

Aminolysis of Y-substituted phenyl diphenylphosphinates and benzoates: Effect of modification of electrophilic center from C=O to P=O

(Chemical Equation Presented) The effect of modification of the electrophilic center from C=O to P=O on reactivity and reaction mechanism has been investigated for aminolysis of Y-substituted phenyl diphenylphosphinates (1a-j) and benzoates (2a-i). The phosphinates 1a-j are less reactive than the benzoates 2a-i. The reactions of 2,4-dinitrophenyl diphenylphosphinate (1a) with alicyclic secondary amines resulted in a linear Bronsted-type plot with a βnuc value of 0.38, while the corresponding reactions of 2,4-dinitrophenyl benzoate (2a) yielded a curved Bronsted-type plot. Similarly, a linear Bronsted-type plot with a β1g value of -0.66 was obtained for the reactions of 1a-j with piperidine, while the corresponding reactions of 2a-i gave a curved Bronsted-type plot. The linear Bronsted-type plots for the reactions of 1a-j have been taken as evidence for a concerted mechanism, while the curved Bronsted-type plots for the reactions of 2a-i have been suggested to indicate a change in the rate-determining step of a stepwise mechanism. The Hammett plot for the reactions of 1b-j exhibited a poor correlation with σ- constants (R2 = 0.962) but slightly better correlation with σo (R2 = 0.986). However, the Yukawa-Tsuno plot for the same reactions resulted in an excellent correlation (R2 = 0.9993) with an r value of 0.30. The aminolysis of 1a-j has been suggested to proceed through a concerted mechanism with an early transition state on the basis of the small βnuc and small r values.