21717-29-3Relevant articles and documents
IMIDAZOPYRIDINES SYK INHIBITORS
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Paragraph 0372, (2014/06/11)
Certain imidazopyridines (I) and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.
ANTI-VIRAL COMPOUNDS
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, (2008/12/08)
Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
Protection of Primary Amines as N-Substituted 2,5-Dimethylpyrroles
Breukelman, Stephen P.,Meakins, G. Denis,Tirel, Malcolm D.
, p. 800 - 801 (2007/10/02)
Protection of a primary amine group against attack by organic or aqueous solutions of strong bases or nucleophiles is achieved by incorporation into an N-substituted 2,5-dimethylpyrrole system from which the amine group is regenerated by treatment with hydroxylamine hydrochloride.