217178-62-6

Basic information

• Product Name: Stampidine
• CAS NO: 217178-62-6
• Molecular Formula: C₂₀H₂₃BrN₃O₈P
• Molecular Weight: 546.312
• Mol File: 217178-62-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Stampidine(CAS DataBase Reference)
• NIST Chemistry Reference: Stampidine(217178-62-6)
• EPA Substance Registry System: Stampidine(217178-62-6)

Safety Data

• Hazardous Substances Data: 217178-62-6(Hazardous Substances Data)

Upstream product

• 19430-76-3 p-bromophenyl phosphorodichloridate 
• 106-41-2 4-bromo-phenol 
• 3056-17-5 stavudin 
• 217090-42-1 4-bromophenyl methoxy-alanyl phosphorochloridate 
• 2491-20-5 L-alanine methyl ester hydrochloride 

Downstream Products

• 106-41-2 4-bromo-phenol 
• 635312-23-1 5'-O-(3'-deoxy-2',3'-didehydrothymidinyl)-O-(4-bromophenyl)-N-[(S)-methoxyalaninyl]-phosphoramidate 
• 635312-24-2 5'-O-(3'-deoxy-2',3'-didehydrothymidinyl)-O-(4-bromophenyl)-N-[(S)-methoxyalaninyl]-phosphoramidate 
• 3056-17-5 stavudin 

Relevant articles and documents

Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: Structural determinants for in vitro activity and QSAR

A series of new substituted-aryl phosphoramidate derivatives of the anti-HIV drug d4T were synthesized as membrane-soluble nucleotide prodrugs, to extend and quantify the SAR observed for an earlier series of related derivatives. All of the compounds were

Large-scale synthesis and formulation of GMP-grade stampidine, a new anti-HIV agent

The arylphosphoramidate derivative of stavudine (STV, d4T, 2',3'-didehydro-3'-deoxythymidine, CAS 3056-17-5), stampidine (STAMP, DDE-113, HI-113, N-[p-(4-bromophenyl)-2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine methyl ester, CAS 217178-62-6), is a n