21719-87-9

Upstream product

• 372-19-0 meta-fluoroaniline 
• 100-47-0 benzonitrile 

Downstream Products

• 82635-77-6 2-({[N¹-(3-Fluoro-phenyl)-benzimidoyl]-amino}-methylene)-malonic acid diethyl ester 
• 89069-61-4 3-(3-fluorophenyl)-2-phenyl-4(3H)-pyrimidinone 
• 1325218-11-8 N-tert-butyl-4-amino-7-fluoro-2-phenylquinazoline 
• 79529-98-9 5-fluoro-2-phenyl-1H-benzo[d]imidazole 
• 82636-01-9 1-(3-Fluoro-phenyl)-6-oxo-2-phenyl-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 89069-77-2 3-(3-fluorophenyl)-2,6-diphenyl-4(3H)-pyrimidinone 

Relevant academic research and scientific papers

Oxidative Cyclization Approach to Benzimidazole Libraries

An efficient approach to the parallel synthesis of benzimidazoles from anilines is described. Library approaches to vary the N1 and C2 vectors of benzimidazoles are well established; however, C4-C7 variation has traditionally relied on 1,2-dianiline build

N-Heterocyclic carbene-catalyzed annulation of ynals with amidines: Access to 1,2,6-trisubstituted pyrimidin-4-ones

An N-heterocyclic carbene-catalyzed annulation of ynals and amidines has been reported to construct pyrimidin-4-ones. The protocol features a broad substrate scope and mild conditions. Furthermore, an oxidative strategy to catalytically generate ynal-deri

Synthesis & Pharmacological Evaluation of Ethyl 3-Substituted-phenyl-2-methylmercapto/ phenyl/ methyl-4(3H)-pyrimidone-5-carboxylates

A number of ethyl 3-substituted-phenyl-2-methylmercapto/ phenyl/ methyl-4(3H)-pyrimidone-5-carboxylates (V) have been prepared by the reaction of amidines (III) with diethyl ethoxymethylenemalonate.In order to confirm the structure (V), ethyl 3-(2'-methylphenyl)-2-methylmercapto-4(3H)pyrimidone-5-carboxylate (103) has been transformed into the earlier synthesised 3-(2'-methylphenyl)-2-methylmercapto-4(3H)-pyrimidone (115) by decarboxylation of 3-(2'-methylphenyl)-2-methylmercapto-4(3H)-pyrimidone-5-carboxylic acid (114), obtained by the alkaline hydrolysis of 103.Someof these compounds have shown antiinflammatory, diuretic and antipassive cutaneous anaphylaxis activities.