217318-85-9Relevant academic research and scientific papers
Discovery of diphenyloxazole and Nδ-Z-ornithine derivatives as highly potent and selective human prostaglandin EP4 receptor antagonists
Hattori, Kouji,Tanaka, Akira,Fujii, Naoaki,Takasugi, Hisashi,Tenda, Yoshiyuki,Tomita, Masayuki,Nakazato, Shoko,Nakano, Keiko,Kato, Yasuko,Kono, Yutaka,Murai, Hidetsugu,Sakane, Kazuo
, p. 3103 - 3106 (2005)
Two novel classes of diphenyloxazole and Nδ-Z-ornithine derivatives as highly potent and selective EP4 antagonists have been discovered. The optimized diphenyloxzole 8 and Nδ-Z-ornithine 11 effectively competed with [3H]-PGE2/s
Oxazole compounds useful as PGE2 agonists and antagonists
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, (2008/06/13)
Azole compounds of the formula: wherein R1 is lower alkyl substituted with carboxy, etc.,R2 is hydrogen or lower alkyl,R3 is aryl, etc.R4 is aryl, etc.Q is ?etc., andX is O, NH or S,and its salt, which are usefu
