217320-91-7

Upstream product

• 917-92-0 3,3-Dimethylbut-1-yne 
• 10458-14-7 (2R,5S)-menthone 
• 37892-71-0 tert-butyllithium 

Downstream Products

• 217321-00-1 (1R,2S,5R)-1-((E)-3,3-Dimethyl-but-1-enyl)-2-isopropyl-5-methyl-cyclohexanol 
• 217321-19-2 {(R)-1-[(2S,5R)-2-Isopropyl-5-methyl-cyclohex-(E)-ylidenemethyl]-2,2-dimethyl-propyl}-benzene 
• 217321-07-8 Carbonic acid (1R,2S,5R)-1-((E)-3,3-dimethyl-but-1-enyl)-2-isopropyl-5-methyl-cyclohexyl ester methyl ester 
• 33124-21-9 (R)-3,3-Dimethyl-2-phenyl-1-butanol 

Relevant academic research and scientific papers

Chiral α-substituted carbonyls and alcohols from the S(N)2' displacement of cuprates on chiral carbonates: An alternative to the alkylation of chiral enolates

A highly stereoselective sequence of reactions, based on the anti-selective S(N)2' addition of cuprates to allylic carbonates, transforms alkynes or alkenyl halides into carbonyls having α-chiral centers. The method, which uses menthone as a chiral auxiliary, is a useful alternative to the alkylation of chiral enolates with the added advantage of allowing for the 'alkylation' of sec- and tert-alkyl and aryl groups.