217448-41-4

Upstream product

• 87954-27-6 1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-indole 
• 153432-70-3 2-(tributylstannyl)-1-<<2-(trimethylsilyl)ethoxy>methyl>-1H-indole 
• 217448-53-8 1-benzyl-5-bromo-1,2-dihydropyridin-2-one 
• 99275-45-3 2-iodo-1-<<2-(trimethylsilyl)ethoxy>methyl>indole 

Relevant academic research and scientific papers

Application of the Pd-catalyzed heteroarylation to the synthesis of 5- (indol-2'-yl)pyridin-2-one and 5-(indol-2'-yl)pyran-2-one

The synthesis of 5-(indol-2'-yl)pyridin-2-ones and 5-(indol-2'-yl)pyran- 2-one by Pd-catalyzed reactions is described. The best results are obtained using 2-indolylstannanes or 2-indolylzinc halides to be coupled with 5- bromopyridin-2-ones or 5-bromopyran-2-one in the presence of Pd(PPh3)4 as catalyst. Other Pd-catalyzed reactions are discussed.